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Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine*.
Jangra, Sonia; De Vrieze, Jana; Choi, Angela; Rathnasinghe, Raveen; Laghlali, Gabriel; Uvyn, Annemiek; Van Herck, Simon; Nuhn, Lutz; Deswarte, Kim; Zhong, Zifu; Sanders, Niek N; Lienenklaus, Stefan; David, Sunil A; Strohmeier, Shirin; Amanat, Fatima; Krammer, Florian; Hammad, Hamida; Lambrecht, Bart N; Coughlan, Lynda; García-Sastre, Adolfo; De Geest, Bruno G; Schotsaert, Michael.
Afiliación
  • Jangra S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • De Vrieze J; Department of Pharmaceutics, Ghent University, Ghent, Belgium.
  • Choi A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Rathnasinghe R; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Laghlali G; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Uvyn A; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Van Herck S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Nuhn L; Department of Pharmaceutics, Ghent University, Ghent, Belgium.
  • Deswarte K; Department of Pharmaceutics, Ghent University, Ghent, Belgium.
  • Zhong Z; Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
  • Sanders NN; Department of Internal Medicine and Pediatrics, Ghent University and VIB Center for Inflammation Research, Zwijnaarde, Belgium.
  • Lienenklaus S; Department of Pharmaceutics, Ghent University, Ghent, Belgium.
  • David SA; Laboratory for Gene Therapy, Ghent University, Merelbeke, Belgium.
  • Strohmeier S; Institute for Laboratory Animal Science, Institute of Immunology, Hannover Medical School, Hannover, Germany.
  • Amanat F; Virovax, Lawrence, KS, USA.
  • Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Hammad H; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Lambrecht BN; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Coughlan L; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • De Geest BG; Department of Internal Medicine and Pediatrics, Ghent University and VIB Center for Inflammation Research, Zwijnaarde, Belgium.
  • Schotsaert M; Department of Internal Medicine and Pediatrics, Ghent University and VIB Center for Inflammation Research, Zwijnaarde, Belgium.
Angew Chem Int Ed Engl ; 60(17): 9467-9473, 2021 04 19.
Article en En | MEDLINE | ID: mdl-33464672
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quinolinas / Adyuvantes Inmunológicos / Vacunas contra la COVID-19 / COVID-19 / Imidazoles / Inmunidad Innata Límite: Animals / Female / Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quinolinas / Adyuvantes Inmunológicos / Vacunas contra la COVID-19 / COVID-19 / Imidazoles / Inmunidad Innata Límite: Animals / Female / Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos