A novel bicyclic 2,4-diaminopyrimidine inhibitor of <i>Streptococcus suis</i> dihydrofolate reductase.

Songsungthong, Warangkhana; Prasopporn, Sunisa; Bohan, Louise; Srimanote, Potjanee; Leartsakulpanich, Ubolsree; Yongkiettrakul, Suganya

A novel bicyclic 2,4-diaminopyrimidine inhibitor of Streptococcus suis dihydrofolate reductase.

Songsungthong, Warangkhana; Prasopporn, Sunisa; Bohan, Louise; Srimanote, Potjanee; Leartsakulpanich, Ubolsree; Yongkiettrakul, Suganya.

Afiliación

Songsungthong W; Biosensing and Bioprospecting Research Group, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Prasopporn S; Biosensing and Bioprospecting Research Group, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Bohan L; Current Address: Department of Pharmacology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Srimanote P; Biosensing and Bioprospecting Research Group, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Leartsakulpanich U; Current Address: School of Pharmacy and Life Sciences, The Robert Gordon University, Aberdeen, United Kingdom.
Yongkiettrakul S; Faculty of Allied Health Sciences, Thammasat University, Klong Luang, Pathum Thani, Thailand.

PeerJ ; 9: e10743, 2021.

Article en En | MEDLINE | ID: mdl-33604179

Palabras clave

Antibiotics; Antifolate; Diaminopyrimidine; Dihydrofolate reductase; Drug discovery; Drug resistant; Growth inhibition; Pathogen Box; Screening; Streptococcus suis

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: PeerJ Año: 2021 Tipo del documento: Article País de afiliación: Tailandia