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Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome.
Kennedy, Alyssa L; Myers, Kasiani C; Bowman, James; Gibson, Christopher J; Camarda, Nicholas D; Furutani, Elissa; Muscato, Gwen M; Klein, Robert H; Ballotti, Kaitlyn; Liu, Shanshan; Harris, Chad E; Galvin, Ashley; Malsch, Maggie; Dale, David; Gansner, John M; Nakano, Taizo A; Bertuch, Alison; Vlachos, Adrianna; Lipton, Jeffrey M; Castillo, Paul; Connelly, James; Churpek, Jane; Edwards, John R; Hijiya, Nobuko; Ho, Richard H; Hofmann, Inga; Huang, James N; Keel, Siobán; Lamble, Adam; Lau, Bonnie W; Norkin, Maxim; Stieglitz, Elliot; Stock, Wendy; Walkovich, Kelly; Boettcher, Steffen; Brendel, Christian; Fleming, Mark D; Davies, Stella M; Weller, Edie A; Bahl, Christopher; Carter, Scott L; Shimamura, Akiko; Lindsley, R Coleman.
Afiliación
  • Kennedy AL; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Myers KC; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Bowman J; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Gibson CJ; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Camarda ND; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Furutani E; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Muscato GM; Institute for Protein Innovation, Boston, MA, USA.
  • Klein RH; Department of Medical Oncology, Division of Hematological Malignancies Dana-Farber Cancer Institute, Boston, MA, USA.
  • Ballotti K; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Liu S; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Harris CE; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Galvin A; Boston Children's Hospital, Boston, MA, USA.
  • Malsch M; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Dale D; Broad Institute, Boston, MA, USA.
  • Gansner JM; Boston Children's Hospital, Boston, MA, USA.
  • Nakano TA; Biostatistics and Research Design Center, Institutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, MA, USA.
  • Bertuch A; Boston Children's Hospital, Boston, MA, USA.
  • Vlachos A; Boston Children's Hospital, Boston, MA, USA.
  • Lipton JM; Boston Children's Hospital, Boston, MA, USA.
  • Castillo P; Department of Internal Medicine, University of Washington, Seattle, WA, USA.
  • Connelly J; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Churpek J; Center for Cancer and Blood Disorders, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, USA.
  • Edwards JR; Department of Pediatrics/Hematology-Oncology, Baylor College of Medicine, Houston, TX, USA.
  • Hijiya N; Division of Hematology/Oncology and Cellular Therapy, Cohen Children's Medical Center of New York, New Hyde Park, NY, USA.
  • Ho RH; Zucker School of Medicine at Hofstra/Northwell School of Medicine, Hempstead, NY, USA.
  • Hofmann I; Division of Hematology/Oncology and Cellular Therapy, Cohen Children's Medical Center of New York, New Hyde Park, NY, USA.
  • Huang JN; Zucker School of Medicine at Hofstra/Northwell School of Medicine, Hempstead, NY, USA.
  • Keel S; Shands Children's Hospital, Department of Pediatrics, Division of Pediatric Hematology Oncology, University of Florida, Gainesville, FL, USA.
  • Lamble A; Department of Pediatrics, Division of Pediatric Hematology Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Lau BW; Department of Medicine, Section of Hematology, Oncology, and Palliative Care, The University of Wisconsin-Madison, Madison, WI, USA.
  • Norkin M; Indiana Blood and Marrow Transplantation, Indianapolis, IN, USA.
  • Stieglitz E; Department of Pediatrics, Columbia University Medical Center, New York, NY, USA.
  • Stock W; Department of Pediatrics, Division of Pediatric Hematology Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Walkovich K; Department of Pediatrics, Division of Pediatric Hematology/Oncology and BMT, University of Wisconsin, Madison, WI, USA.
  • Boettcher S; Department of Pediatrics, UCSF Benioff Children's Hospital, San Francisco, CA, USA.
  • Brendel C; Division of Pediatric Allergy, Immunology, and Blood & Marrow Transplantation, UCSF Benioff Children's Hospital, San Francisco, CA, USA.
  • Fleming MD; Division of Hematology, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Davies SM; Division of Hematology-Oncology, Seattle Children's Hospital, Seattle, WA, USA.
  • Weller EA; Dartmouth-Hitchcock Medical Center, Pediatric Hematology Oncology, Geisel School of Medicine, Lebanon, NH, USA.
  • Bahl C; Department of Medicine, University of Florida, Gainesville, FL, USA.
  • Carter SL; Division of Cancer Medicine, Baptist MD Anderson Cancer Center, Jacksonville, FL, USA.
  • Shimamura A; Department of Pediatrics, UCSF Benioff Children's Hospital, San Francisco, CA, USA.
  • Lindsley RC; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.
Nat Commun ; 12(1): 1334, 2021 02 26.
Article en En | MEDLINE | ID: mdl-33637765

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Síndrome de Shwachman-Diamond / Hematopoyesis Clonal Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Síndrome de Shwachman-Diamond / Hematopoyesis Clonal Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos