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mTORC1 promotes cell growth via m6A-dependent mRNA degradation.
Cho, Sungyun; Lee, Gina; Pickering, Brian F; Jang, Cholsoon; Park, Jin H; He, Long; Mathur, Lavina; Kim, Seung-Soo; Jung, Sunhee; Tang, Hong-Wen; Monette, Sebastien; Rabinowitz, Joshua D; Perrimon, Norbert; Jaffrey, Samie R; Blenis, John.
Afiliación
  • Cho S; Department of Pharmacology, Meyer Cancer Center, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Lee G; Department of Pharmacology, Meyer Cancer Center, Weill Cornell Medicine, Cornell University, New York, NY, USA; Department of Microbiology and Molecular Genetics, Chao Family Comprehensive Cancer Center, University of California Irvine School of Medicine, Irvine, CA, USA. Electronic address: ginalee
  • Pickering BF; Department of Pharmacology, Meyer Cancer Center, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Jang C; Department of Chemistry, Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA; Department of Biological Chemistry, Chao Family Comprehensive Cancer Center, University of California Irvine School of Medicine, Irvine, CA, USA.
  • Park JH; Department of Pharmacology, Meyer Cancer Center, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • He L; Department of Pharmacology, Meyer Cancer Center, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Mathur L; Department of Microbiology and Molecular Genetics, Chao Family Comprehensive Cancer Center, University of California Irvine School of Medicine, Irvine, CA, USA.
  • Kim SS; Department of Obstetrics and Gynecology, Irving Medical Center, Columbia University, New York, NY, USA.
  • Jung S; Department of Biological Chemistry, Chao Family Comprehensive Cancer Center, University of California Irvine School of Medicine, Irvine, CA, USA.
  • Tang HW; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.
  • Monette S; Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, The Rockefeller University, Weill Cornell Medicine, New York, NY, USA.
  • Rabinowitz JD; Department of Chemistry, Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
  • Perrimon N; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA; Howard Hughes Medical Institute, Boston, MA, USA.
  • Jaffrey SR; Department of Pharmacology, Meyer Cancer Center, Weill Cornell Medicine, Cornell University, New York, NY, USA. Electronic address: srj2003@med.cornell.edu.
  • Blenis J; Department of Pharmacology, Meyer Cancer Center, Weill Cornell Medicine, Cornell University, New York, NY, USA. Electronic address: job2064@med.cornell.edu.
Mol Cell ; 81(10): 2064-2075.e8, 2021 05 20.
Article en En | MEDLINE | ID: mdl-33756105

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Adenosina / Estabilidad del ARN / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Adenosina / Estabilidad del ARN / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos