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PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway.
Wang, Mei-Sa; Han, Qiu-Shuang; Jia, Zhi-Rong; Chen, Chuan-Sheng; Qiao, Chen; Liu, Qian-Qian; Zhang, Ya-Meng; Wang, Kai-Wei; Wang, Jie; Xiao, Kang; Ding, Xuan-Sheng.
Afiliación
  • Wang MS; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
  • Han QS; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
  • Jia ZR; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
  • Chen CS; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
  • Qiao C; Precision Medicine Laboratory, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
  • Liu QQ; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
  • Zhang YM; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
  • Wang KW; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
  • Wang J; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
  • Xiao K; Department of Pharmacy, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, China.
  • Ding XS; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Acta Pharmacol Sin ; 43(1): 167-176, 2022 Jan.
Article en En | MEDLINE | ID: mdl-33772142
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fenofibrato / Carcinoma de Pulmón de Células no Pequeñas / Gefitinib / Neoplasias Pulmonares / Hipolipemiantes / Antineoplásicos Límite: Humans Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fenofibrato / Carcinoma de Pulmón de Células no Pequeñas / Gefitinib / Neoplasias Pulmonares / Hipolipemiantes / Antineoplásicos Límite: Humans Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China