Solid Plateletrich Plasma Combined with Silicone-hydrogel Soft Contact Lens for Non-healing Corneal Ulcers: A Case Series.
Ocul Immunol Inflamm
; 30(5): 1123-1128, 2022 Jul.
Article
en En
| MEDLINE
| ID: mdl-33793367
ABSTRACT
PURPOSE:
To present a case series of non-healing corneal ulcers treated by solid activated platelet-rich plasma (PRP) combined with silicone-hydrogel soft contact lens.METHODS:
Three eyes from three patients with unresponsive corneal ulcers were included. A clot of PRP was applied directly onto the corneal ulcer and covered with a soft contact lens. The primary outcome was corneal healing. Changes in corneal ulcer area were measured by analyzing slit-lamp photographs taken using ImageJ software.RESULTS:
Successful corneal healing was achieved in all patients within two weeks, with no recurrences or signs of infection through the last follow-up. In two of the three cases, treatment was applied twice.CONCLUSIONS:
This novel procedure was easy to perform, economically advantageous, and a possible alternative to surgical approaches for enhancing epithelial wound healing in patients with non-healing corneal ulcers. Further prospective and comparative studies are needed to assess the efficacy of this treatment.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Úlcera de la Córnea
/
Lentes de Contacto Hidrofílicos
/
Plasma Rico en Plaquetas
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Ocul Immunol Inflamm
Asunto de la revista:
ALERGIA E IMUNOLOGIA
/
OFTALMOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
México