Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion.

Zhu, Chen; Dixon, Karen O; Newcomer, Kathleen; Gu, Guangxiang; Xiao, Sheng; Zaghouani, Sarah; Schramm, Markus A; Wang, Chao; Zhang, Huiyuan; Goto, Kouichiro; Christian, Elena; Rangachari, Manu; Rosenblatt-Rosen, Orit; Okada, Hitoshi; Mak, Tak; Singer, Meromit; Regev, Aviv; Kuchroo, Vijay

Zhu, Chen; Dixon, Karen O; Newcomer, Kathleen; Gu, Guangxiang; Xiao, Sheng; Zaghouani, Sarah; Schramm, Markus A; Wang, Chao; Zhang, Huiyuan; Goto, Kouichiro; Christian, Elena; Rangachari, Manu; Rosenblatt-Rosen, Orit; Okada, Hitoshi; Mak, Tak; Singer, Meromit; Regev, Aviv; Kuchroo, Vijay.

Afiliación

Zhu C; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Dixon KO; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Newcomer K; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Gu G; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
Xiao S; Department of Data Sciences, DFCI, Boston, MA 02215, USA.
Zaghouani S; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Schramm MA; Celsius Therapeutics, Cambridge, MA 02139, USA.
Wang C; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Zhang H; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Goto K; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Christian E; Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Rangachari M; The Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, University of Health Network, Toronto, Ontario M5G 2M9, Canada.
Rosenblatt-Rosen O; Department of Data Sciences, DFCI, Boston, MA 02215, USA.
Okada H; Axe Neurosciences, Centre de recherche du CHU de Québec-Université Laval, QC, Québec, Canada.
Mak T; Department of Molecular Medicine, Faculty of Medicine, Laval University, Québec, QC, Canada.
Singer M; Department of Data Sciences, DFCI, Boston, MA 02215, USA.
Regev A; Department of Biochemistry, Kindai University Faculty of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan.
Kuchroo V; The Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, University of Health Network, Toronto, Ontario M5G 2M9, Canada.

Sci Adv ; 7(18)2021 04.

Article en En | MEDLINE | ID: mdl-33931442

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Sci Adv Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos