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Blocking glutamate mGlu5 receptors with the negative allosteric modulator CTEP improves disease course in SOD1G93A mouse model of amyotrophic lateral sclerosis.
Milanese, Marco; Bonifacino, Tiziana; Torazza, Carola; Provenzano, Francesca; Kumar, Mandeep; Ravera, Silvia; Zerbo, Arianna Roberta; Frumento, Giulia; Balbi, Matilde; Nguyen, T P Nhung; Bertola, Nadia; Ferrando, Sara; Viale, Maurizio; Profumo, Aldo; Bonanno, Giambattista.
Afiliación
  • Milanese M; Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.
  • Bonifacino T; Inter-University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Genoa, Italy.
  • Torazza C; Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.
  • Provenzano F; Inter-University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Genoa, Italy.
  • Kumar M; Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.
  • Ravera S; Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.
  • Zerbo AR; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen and German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Frumento G; Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.
  • Balbi M; Department of Experimental Medicine, University of Genoa, Genoa, Italy.
  • Nguyen TPN; Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.
  • Bertola N; Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.
  • Ferrando S; Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.
  • Viale M; Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy.
  • Profumo A; Department of Experimental Medicine, University of Genoa, Genoa, Italy.
  • Bonanno G; Department of Earth, Environmental and Life Science, University of Genoa, Genoa, Italy.
Br J Pharmacol ; 178(18): 3747-3764, 2021 09.
Article en En | MEDLINE | ID: mdl-33931856
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Br J Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Italia
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Br J Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Italia