Synergistic effects of BKM120 and panobinostat on pre-B acute lymphoblastic cells: an emerging perspective for the simultaneous inhibition of PI3K and HDACs.

Mehrpouri, Mahdieh; Momeny, Majid; Bashash, Davood

Mehrpouri, Mahdieh; Momeny, Majid; Bashash, Davood.

Afiliación

Mehrpouri M; Department of Laboratory Sciences, School of Allied Medical Sciences, Alborz University of Medical Sciences, Karaj, Iran.
Momeny M; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.
Bashash D; Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

J Recept Signal Transduct Res ; 42(1): 100-108, 2022 Feb.

Article en En | MEDLINE | ID: mdl-33969806

Asunto(s)

Antineoplásicos; Fosfatidilinositol 3-Quinasas; Aminopiridinas/farmacología; Antineoplásicos/farmacología; Apoptosis; Línea Celular Tumoral; Histona Desacetilasas/genética; Humanos; Morfolinas; Panobinostat/farmacología

Palabras clave

Acute lymphoblastic leukemia; BKM120; PI3K signaling pathway; histone deacetylase (HDAC); panobinostat

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fosfatidilinositol 3-Quinasas / Antineoplásicos Límite: Humans Idioma: En Revista: J Recept Signal Transduct Res Asunto de la revista: BIOQUIMICA / FISIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Irán

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