Dehydrocrenatidine inhibits head and neck cancer cells invasion and migration by modulating JNK1/2 and ERK1/2 pathway and decreases MMP-2 expression.

Velmurugan, Bharath Kumar; Lin, Jen-Tsun; Mahalakshmi, B; Lin, Chia-Chieh; Chuang, Yi-Ching; Lo, Yu-Sheng; Ho, Hsin-Yu; Hsieh, Ming-Ju; Chen, Mu-Kuan

Velmurugan, Bharath Kumar; Lin, Jen-Tsun; Mahalakshmi, B; Lin, Chia-Chieh; Chuang, Yi-Ching; Lo, Yu-Sheng; Ho, Hsin-Yu; Hsieh, Ming-Ju; Chen, Mu-Kuan.

Afiliación

Velmurugan BK; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.
Lin JT; Division of Hematology and Oncology, Department of Medicine, Changhua Christian Hospital, Changhua, Taiwan.
Mahalakshmi B; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Lin CC; Post Baccalaureate Medicine, National Chung Hsing University, Taichung, Taiwan.
Chuang YC; Department of Research and Development, Vels Publishers, Tamilnadu, India.
Lo YS; Oral Cancer Research Center, Changhua Christian Hospital, Changhua, Taiwan.
Ho HY; Oral Cancer Research Center, Changhua Christian Hospital, Changhua, Taiwan.
Hsieh MJ; Oral Cancer Research Center, Changhua Christian Hospital, Changhua, Taiwan.
Chen MK; Oral Cancer Research Center, Changhua Christian Hospital, Changhua, Taiwan.

Environ Toxicol ; 36(9): 1848-1856, 2021 Sep.

Article en En | MEDLINE | ID: mdl-34076342

Asunto(s)

Neoplasias de Cabeza y Cuello; Metaloproteinasa 2 de la Matriz; Carbolinas; Línea Celular Tumoral; Movimiento Celular; Humanos; Sistema de Señalización de MAP Quinasas; Metaloproteinasa 2 de la Matriz/genética; Metaloproteinasa 2 de la Matriz/metabolismo; Proteína Quinasa 8 Activada por Mitógenos/metabolismo; Proteína Quinasa 9 Activada por Mitógenos/metabolismo; Invasividad Neoplásica

Palabras clave

MMP; dehydrocrenatidine; head and neck cancer; invasion; migration

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Metaloproteinasa 2 de la Matriz / Neoplasias de Cabeza y Cuello Límite: Humans Idioma: En Revista: Environ Toxicol Asunto de la revista: SAUDE AMBIENTAL / TOXICOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Taiwán

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