Ranking Biomarkers of Aging by Citation Profiling and Effort Scoring.
Front Genet
; 12: 686320, 2021.
Article
en En
| MEDLINE
| ID: mdl-34093670
ABSTRACT
Aging affects most living organisms and includes the processes that reduce health and survival. The chronological and the biological age of individuals can differ remarkably, and there is a lack of reliable biomarkers to monitor the consequences of aging. In this review we give an overview of commonly mentioned and frequently used potential aging-related biomarkers. We were interested in biomarkers of aging in general and in biomarkers related to cellular senescence in particular. To answer the question whether a biological feature is relevant as a potential biomarker of aging or senescence in the scientific community we used the PICO strategy known from evidence-based medicine. We introduced two scoring systems, aimed at reflecting biomarker relevance and measurement effort, which can be used to support study designs in both clinical and research settings.
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MEDLINE
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Revista:
Front Genet
Año:
2021
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Article
País de afiliación:
Alemania