SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression.

Zhou, Haibin; Bai, Longchuan; Xu, Renqi; McEachern, Donna; Chinnaswamy, Krishnapriya; Li, Ruiting; Wen, Bo; Wang, Mi; Yang, Chao-Yie; Meagher, Jennifer L; Sun, Duxin; Stuckey, Jeanne A; Wang, Shaomeng

Zhou, Haibin; Bai, Longchuan; Xu, Renqi; McEachern, Donna; Chinnaswamy, Krishnapriya; Li, Ruiting; Wen, Bo; Wang, Mi; Yang, Chao-Yie; Meagher, Jennifer L; Sun, Duxin; Stuckey, Jeanne A; Wang, Shaomeng.

Afiliación

Zhou H; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
Bai L; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
Xu R; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
McEachern D; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
Chinnaswamy K; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
Li R; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
Wen B; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
Wang M; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
Yang CY; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
Meagher JL; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
Sun D; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
Stuckey JA; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
Wang S; Rogel Cancer Center, Departments of Internal Medicine and Pharmacology, Medical School, Medicinal Chemistry, College of Pharmacy, Life Sciences Institute, Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.

ACS Med Chem Lett ; 12(6): 996-1004, 2021 Jun 10.

Article en En | MEDLINE | ID: mdl-34141084

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: ACS Med Chem Lett Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos