Vascular and Lymphatic Malformations: Perspectives From Human and Vertebrate Studies.
Circ Res
; 129(1): 131-135, 2021 06 25.
Article
en En
| MEDLINE
| ID: mdl-34166069
ABSTRACT
Vascular malformations, affecting ≈1% to 1.5% of the population, comprise a spectrum of developmental patterning defects of capillaries, arteries, veins, and/or lymphatics. The majority of vascular malformations occur sporadically; however, inherited malformations exist as a part of complex congenital diseases. The malformations, ranging from birthmarks to life-threatening conditions, are present at birth, but may reveal signs and symptoms-including pain, bleeding, disfigurement, and functional defects of vital organs-in infancy, childhood, or adulthood. Vascular malformations often exhibit recurrent patterns at affected sites due to the lack of curative treatments. This review series provides a state-of-the-art assessment of vascular malformation research at basic, clinical, genetic, and translational levels.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Vasos Sanguíneos
/
Vasos Linfáticos
/
Anomalías Linfáticas
/
Malformaciones Vasculares
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Circ Res
Año:
2021
Tipo del documento:
Article