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Dual targeting of MEK and PI3K effectively controls the proliferation of human EGFR-TKI resistant non-small cell lung carcinoma cell lines with different genetic backgrounds.
Qu, Ge-Ping; Shi, Min; Wang, Dan; Wu, Jiong-He; Wang, Peng; Gong, Mei-Liang; Zhang, Zhi-Jian.
Afiliación
  • Qu GP; Department of Respiratory and Critical Care Medicine, Second Medical Center of Chinese PLA General Hospital, No. 28 of Fuxing Street, Haidian District, Beijing, 100853, China.
  • Shi M; Department of Respiratory and Critical Care Medicine, Second Medical Center of Chinese PLA General Hospital, No. 28 of Fuxing Street, Haidian District, Beijing, 100853, China.
  • Wang D; Department of Respiratory and Critical Care Medicine, Second Medical Center of Chinese PLA General Hospital, No. 28 of Fuxing Street, Haidian District, Beijing, 100853, China.
  • Wu JH; Department of Respiratory and Critical Care Medicine, Second Medical Center of Chinese PLA General Hospital, No. 28 of Fuxing Street, Haidian District, Beijing, 100853, China.
  • Wang P; Department of Respiratory and Critical Care Medicine, Second Medical Center of Chinese PLA General Hospital, No. 28 of Fuxing Street, Haidian District, Beijing, 100853, China.
  • Gong ML; Department of Laboratory Diagnosis, Second Medical Center of Chinese, PLA General Hospital, Beijing, 100853, China.
  • Zhang ZJ; Department of Respiratory and Critical Care Medicine, Second Medical Center of Chinese PLA General Hospital, No. 28 of Fuxing Street, Haidian District, Beijing, 100853, China. zhangzhijian66_as@163.com.
BMC Pulm Med ; 21(1): 208, 2021 Jul 01.
Article en En | MEDLINE | ID: mdl-34210314
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Morfolinas / Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Quinasas de Proteína Quinasa Activadas por Mitógenos / Afatinib / Aminopiridinas / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: BMC Pulm Med Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Morfolinas / Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Quinasas de Proteína Quinasa Activadas por Mitógenos / Afatinib / Aminopiridinas / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: BMC Pulm Med Año: 2021 Tipo del documento: Article País de afiliación: China