Neutrophils as an emerging therapeutic target and tool for cancer therapy.
Life Sci
; 285: 119952, 2021 Nov 15.
Article
en En
| MEDLINE
| ID: mdl-34520766
ABSTRACT
Activation of neutrophils is necessary for the protection of the host against microbial infection. This property can be used as mode of therapy for cancer treatment. Neutrophils have conflicting dual functions in cancer as either a tumor promoter or inhibitor. Neutrophil-based drug delivery has achieved increased attention in pre-clinical models. This review addresses in detail the different neutrophil constituents, the conflicting function of neutrophils and activation of the neutrophil as an important target of therapy for cancer treatment, and use of neutrophils or neutrophil membrane-derived vesicles as vehicles for drug delivery and targeting.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Portadores de Fármacos
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Terapia de Inmunosupresión
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Activación Neutrófila
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Terapia Molecular Dirigida
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Neoplasias
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Neutrófilos
Límite:
Humans
Idioma:
En
Revista:
Life Sci
Año:
2021
Tipo del documento:
Article