IL-18 binding protein suppresses IL-17-induced osteoclastogenesis and rectifies type 17 helper T cell / regulatory T cell imbalance in rheumatoid arthritis.

Min, Hong Ki; Kim, Sehee; Lee, Ji-Yeon; Kim, Kyoung-Woon; Lee, Sang-Heon; Kim, Hae-Rim

Min, Hong Ki; Kim, Sehee; Lee, Ji-Yeon; Kim, Kyoung-Woon; Lee, Sang-Heon; Kim, Hae-Rim.

Afiliación

Min HK; Division of Rheumatology, Department of Internal Medicine, Konkuk University Medical Center, Seoul, 05030, Republic of Korea.
Kim S; Division of Rheumatology, Department of Internal Medicine, Konkuk University Medical Center, Seoul, 05030, Republic of Korea.
Lee JY; The Rheumatism Research Center, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, 05030, Republic of Korea.
Kim KW; R&D Center, OncoInsight, Seoul, 06373, Republic of Korea.
Lee SH; Division of Rheumatology, Department of Internal Medicine, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, 05030, Republic of Korea.
Kim HR; Division of Rheumatology, Department of Internal Medicine, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, 05030, Republic of Korea. kimhaerim@kuh.ac.kr.

J Transl Med ; 19(1): 392, 2021 09 16.

Article en En | MEDLINE | ID: mdl-34530864

Asunto(s)

Artritis Reumatoide; Interleucina-17; Células Cultivadas; Humanos; Péptidos y Proteínas de Señalización Intercelular; Leucocitos Mononucleares; Osteoclastos; Osteogénesis; Ligando RANK; Linfocitos T Reguladores; Células Th17

Palabras clave

Interleukin-18 binding protein; Osteoclastogenesis; Regulatory T cell; Rheumatoid arthritis; Type 17 helper T cell

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Artritis Reumatoide / Interleucina-17 Límite: Humans Idioma: En Revista: J Transl Med Año: 2021 Tipo del documento: Article

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