Immunoregulatory T cell epitope peptides for the treatment of allergic disease.
Immunotherapy
; 13(15): 1283-1291, 2021 10.
Article
en En
| MEDLINE
| ID: mdl-34558985
Lay abstract Allergen immunotherapy is the only disease-modifying treatment option for patients with chronic allergic rhinitis, typically featuring formulations to promote the development of immune tolerance. Although effective, the use of whole allergen has been found to promote unintended IgE crosslinking, resulting in local and systemic adverse effects. To overcome such limitations, the use of T-cell epitope peptides in allergen immunotherapy has been explored with hopeful outcomes. Compared with allergen immunotherapy, peptide immunotherapy is quicker, safer and more efficacious, making it quite promising. Although peptides for pet dander, honeybee venom, pollen and house dust mite allergies have been developed, more extensive research is necessary to prior to widespread usage.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Hipersensibilidad Respiratoria
/
Desensibilización Inmunológica
/
Epítopos de Linfocito T
Tipo de estudio:
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Immunotherapy
Asunto de la revista:
ALERGIA E IMUNOLOGIA
/
TERAPEUTICA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Canadá