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Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.
Mikhaylova, Anna V; McHugh, Caitlin P; Polfus, Linda M; Raffield, Laura M; Boorgula, Meher Preethi; Blackwell, Thomas W; Brody, Jennifer A; Broome, Jai; Chami, Nathalie; Chen, Ming-Huei; Conomos, Matthew P; Cox, Corey; Curran, Joanne E; Daya, Michelle; Ekunwe, Lynette; Glahn, David C; Heard-Costa, Nancy; Highland, Heather M; Hobbs, Brian D; Ilboudo, Yann; Jain, Deepti; Lange, Leslie A; Miller-Fleming, Tyne W; Min, Nancy; Moon, Jee-Young; Preuss, Michael H; Rosen, Jonathon; Ryan, Kathleen; Smith, Albert V; Sun, Quan; Surendran, Praveen; de Vries, Paul S; Walter, Klaudia; Wang, Zhe; Wheeler, Marsha; Yanek, Lisa R; Zhong, Xue; Abecasis, Goncalo R; Almasy, Laura; Barnes, Kathleen C; Beaty, Terri H; Becker, Lewis C; Blangero, John; Boerwinkle, Eric; Butterworth, Adam S; Chavan, Sameer; Cho, Michael H; Choquet, Hélène; Correa, Adolfo; Cox, Nancy.
Afiliación
  • Mikhaylova AV; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA.
  • McHugh CP; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA.
  • Polfus LM; Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
  • Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Boorgula MP; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Blackwell TW; TOPMed Informatics Research Center, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98105, USA.
  • Broome J; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA.
  • Chami N; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA.
  • Chen MH; Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, MD 20892, USA; National Heart, Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA.
  • Conomos MP; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA.
  • Cox C; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78539, USA.
  • Daya M; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Ekunwe L; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA.
  • Glahn DC; Department of Psychiatry, Boston Children's Hospital and Harvard Medical School, Boston, MA 02155, USA.
  • Heard-Costa N; National Heart, Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01701, USA; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA.
  • Highland HM; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Hobbs BD; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Ilboudo Y; Montréal Heart Institute, Montréal, Québec H1T 1C8, Canada; Faculté de Médecine, Université de Montréal, Montréal, Québec H1T 1C8, Canada.
  • Jain D; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA.
  • Lange LA; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Miller-Fleming TW; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37240, USA.
  • Min N; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA.
  • Moon JY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Preuss MH; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA.
  • Rosen J; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Ryan K; Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Smith AV; TOPMed Informatics Research Center, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Sun Q; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Surendran P; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge CB1 8RN, UK; Health Data Research UK Cambridge, Wellcome
  • de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Walter K; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.
  • Wang Z; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA.
  • Wheeler M; Department of Genome Sciences, University of Washington, Seattle, WA 98105, USA.
  • Yanek LR; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Zhong X; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37240, USA.
  • Abecasis GR; TOPMed Informatics Research Center, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Almasy L; Department of Biomedical and Health Informatics, the Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
  • Barnes KC; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Beaty TH; School of Public Health, John Hopkins University, Baltimore, MD 21205, USA.
  • Becker LC; Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78539, USA.
  • Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge CB1 8RN, UK; Health Data Research UK Cambridge, Wellcome
  • Chavan S; Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Cho MH; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Choquet H; Division of Research, Kaiser Permanente Northern California, Oakland, CA 94601, USA.
  • Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA.
  • Cox N; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37240, USA.
Am J Hum Genet ; 108(10): 1836-1851, 2021 10 07.
Article en En | MEDLINE | ID: mdl-34582791

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Asma / Biomarcadores / Polimorfismo de Nucleótido Simple / Enfermedad Pulmonar Obstructiva Crónica / Sitios de Carácter Cuantitativo / Dermatitis Atópica / Leucocitos Tipo de estudio: Prognostic_studies Límite: Humans País/Región como asunto: America do norte / Europa Idioma: En Revista: Am J Hum Genet Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Asma / Biomarcadores / Polimorfismo de Nucleótido Simple / Enfermedad Pulmonar Obstructiva Crónica / Sitios de Carácter Cuantitativo / Dermatitis Atópica / Leucocitos Tipo de estudio: Prognostic_studies Límite: Humans País/Región como asunto: America do norte / Europa Idioma: En Revista: Am J Hum Genet Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos