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A NOS1AP gene variant is associated with a paradoxical increase of the QT-interval shortening effect of digoxin.
Soroush, Negin; Aarnoudse, Albert-Jan; Kavousi, Maryam; Kors, Jan A; Ikram, M Arfan; Newton-Cheh, Christopher; Ahmadizar, Fariba; Stricker, Bruno H.
Afiliación
  • Soroush N; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Aarnoudse AJ; Department of Internal Medicine, Catharina Hospital, Eindhoven, The Netherlands.
  • Kavousi M; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Kors JA; Department of Medical Informatics, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Ikram MA; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Newton-Cheh C; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Ahmadizar F; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Stricker BH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Pharmacogenomics J ; 22(1): 55-61, 2022 02.
Article en En | MEDLINE | ID: mdl-34616002

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Síndrome de QT Prolongado / Cardiotónicos / Proteínas Adaptadoras Transductoras de Señales / Digoxina Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacogenomics J Asunto de la revista: BIOLOGIA MOLECULAR / FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Síndrome de QT Prolongado / Cardiotónicos / Proteínas Adaptadoras Transductoras de Señales / Digoxina Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacogenomics J Asunto de la revista: BIOLOGIA MOLECULAR / FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos