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CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer.
Gutiontov, Stanley I; Turchan, William Tyler; Spurr, Liam F; Rouhani, Sherin J; Chervin, Carolina Soto; Steinhardt, George; Lager, Angela M; Wanjari, Pankhuri; Malik, Renuka; Connell, Philip P; Chmura, Steven J; Juloori, Aditya; Hoffman, Philip C; Ferguson, Mark K; Donington, Jessica S; Patel, Jyoti D; Vokes, Everett E; Weichselbaum, Ralph R; Bestvina, Christine M; Segal, Jeremy P; Pitroda, Sean P.
Afiliación
  • Gutiontov SI; Department of Radiation and Cellular Oncology, The University of Chicago, 5758 S Maryland Ave, MC 9006, Chicago, IL, 60637, USA.
  • Turchan WT; Department of Radiation and Cellular Oncology, The University of Chicago, 5758 S Maryland Ave, MC 9006, Chicago, IL, 60637, USA.
  • Spurr LF; Pritzker School of Medicine, The University of Chicago, Chicago, IL, USA.
  • Rouhani SJ; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL, USA.
  • Chervin CS; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL, USA.
  • Steinhardt G; Department of Pathology, The University of Chicago, Chicago, IL, USA.
  • Lager AM; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL, USA.
  • Wanjari P; Department of Pathology, The University of Chicago, Chicago, IL, USA.
  • Malik R; Department of Radiation and Cellular Oncology, The University of Chicago, 5758 S Maryland Ave, MC 9006, Chicago, IL, 60637, USA.
  • Connell PP; Department of Radiation and Cellular Oncology, The University of Chicago, 5758 S Maryland Ave, MC 9006, Chicago, IL, 60637, USA.
  • Chmura SJ; Department of Radiation and Cellular Oncology, The University of Chicago, 5758 S Maryland Ave, MC 9006, Chicago, IL, 60637, USA.
  • Juloori A; Department of Radiation and Cellular Oncology, The University of Chicago, 5758 S Maryland Ave, MC 9006, Chicago, IL, 60637, USA.
  • Hoffman PC; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL, USA.
  • Ferguson MK; Section of Thoracic Surgery, Department of Surgery, The University of Chicago, Chicago, IL, USA.
  • Donington JS; Section of Thoracic Surgery, Department of Surgery, The University of Chicago, Chicago, IL, USA.
  • Patel JD; Section of Hematology/Oncology, Department of Medicine, Northwestern University, Evanston, IL, USA.
  • Vokes EE; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL, USA.
  • Weichselbaum RR; Department of Radiation and Cellular Oncology, The University of Chicago, 5758 S Maryland Ave, MC 9006, Chicago, IL, 60637, USA.
  • Bestvina CM; Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, USA.
  • Segal JP; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL, USA.
  • Pitroda SP; Department of Pathology, The University of Chicago, Chicago, IL, USA.
Sci Rep ; 11(1): 20059, 2021 10 08.
Article en En | MEDLINE | ID: mdl-34625620
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Biomarcadores de Tumor / Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Inhibidor p16 de la Quinasa Dependiente de Ciclina / Mutación con Pérdida de Función / Inmunoterapia / Neoplasias Pulmonares Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Biomarcadores de Tumor / Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Inhibidor p16 de la Quinasa Dependiente de Ciclina / Mutación con Pérdida de Función / Inmunoterapia / Neoplasias Pulmonares Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos