Severe respiratory viral infections in children with history of asymptomatic or mild COVID-19.
Pediatr Pulmonol
; 57(2): 361-366, 2022 02.
Article
en En
| MEDLINE
| ID: mdl-34741579
ABSTRACT
IMPORTANCE The spectrum of complications of COVID-19 in children, including the effect of COVID-19 on later viral infection, is not known. OBJECTIVE:
To examine the features of children hospitalized for respiratory illness with history of prior COVID-19.DESIGN:
Retrospective observational case series at a single pediatric quaternary medical center in New York City. Data were obtained from review of medical records.PARTICIPANTS:
Children with prior mild or asymptomatic COVID-19 and no known risk factors for severe respiratory disease, who were hospitalized at our center for acute respiratory illness from October 2020 to May 2021, were reviewed. MAIN OUTCOMES ANDMEASURES:
Co-morbidities, history of prior COVID-19 symptoms, respiratory viral panel findings, acuity of illness, degree of respiratory decompensation based on support and interventions required, duration of hospitalization, and overall clinical course were assessed from the medical record.RESULTS:
This study included 5 patients (median age, 4 years; age range 0.8-9 years; 4 [80%] male). All had positive COVID-19 serology, 1 (20%) had mild symptoms, while the others had no symptoms of prior Sars-CoV-2 infection, 3 (60%) had asthma, and the remaining had no co-morbidities. All were admitted between April and May 2021. Two were re-admitted for respiratory symptoms in the subsequent 3 months. CONCLUSIONS AND RELEVANCE This case series describes a possible association between severe lower respiratory tract infection and prior mild COVID-19 in children. Larger cohort studies describing the respiratory effects of prior COVID-19 in children are needed.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Virosis
/
COVID-19
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Child
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Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
En
Revista:
Pediatr Pulmonol
Asunto de la revista:
PEDIATRIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Estados Unidos