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Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells.
Beyer, Mandy; Henninger, Sven J; Haehnel, Patricia S; Mustafa, Al-Hassan M; Gurdal, Ece; Schubert, Bastian; Christmann, Markus; Sellmer, Andreas; Mahboobi, Siavosh; Drube, Sebastian; Sippl, Wolfgang; Kindler, Thomas; Krämer, Oliver H.
Afiliación
  • Beyer M; Department of Toxicology, University Medical Center, 55131 Mainz, Germany.
  • Henninger SJ; Department of Toxicology, University Medical Center, 55131 Mainz, Germany.
  • Haehnel PS; Department of Hematology, Medical Oncology, and Pneumology, University Medical Center, 55131 Mainz, Germany; University Cancer Center, University Medical Center, Mainz, Germany; German Consortia for Translational Cancer Research, 55131 Mainz, Germany.
  • Mustafa AM; Department of Toxicology, University Medical Center, 55131 Mainz, Germany; Department of Zoology, Faculty of Science, Aswan University, Aswan, Egypt.
  • Gurdal E; Institute for Pharmacy, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Strasse 3, 06120 Halle (Saale), Germany; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, Atasehir, Istanbul 34755, Turkey.
  • Schubert B; Department of Toxicology, University Medical Center, 55131 Mainz, Germany.
  • Christmann M; Department of Toxicology, University Medical Center, 55131 Mainz, Germany.
  • Sellmer A; Institute of Pharmacy, Department of Pharmaceutical/Medicinal Chemistry I, University of Regensburg, 93053 Regensburg, Germany.
  • Mahboobi S; Institute of Pharmacy, Department of Pharmaceutical/Medicinal Chemistry I, University of Regensburg, 93053 Regensburg, Germany.
  • Drube S; Institute of Immunology, Jena University Hospital, 07743 Jena, Germany.
  • Sippl W; Institute for Pharmacy, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Strasse 3, 06120 Halle (Saale), Germany.
  • Kindler T; Department of Hematology, Medical Oncology, and Pneumology, University Medical Center, 55131 Mainz, Germany; University Cancer Center, University Medical Center, Mainz, Germany; German Consortia for Translational Cancer Research, 55131 Mainz, Germany.
  • Krämer OH; Department of Toxicology, University Medical Center, 55131 Mainz, Germany. Electronic address: okraemer@uni-mainz.de.
Cell Chem Biol ; 29(3): 398-411.e4, 2022 03 17.
Article en En | MEDLINE | ID: mdl-34762849
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Inhibidores de Proteínas Quinasas / Tirosina Quinasa 3 Similar a fms Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Cell Chem Biol Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Inhibidores de Proteínas Quinasas / Tirosina Quinasa 3 Similar a fms Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Cell Chem Biol Año: 2022 Tipo del documento: Article País de afiliación: Alemania