De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.

Chen, Kai-En; Guo, Qian; Hill, Timothy A; Cui, Yi; Kendall, Amy K; Yang, Zhe; Hall, Ryan J; Healy, Michael D; Sacharz, Joanna; Norwood, Suzanne J; Fonseka, Sachini; Xie, Boyang; Reid, Robert C; Leneva, Natalya; Parton, Robert G; Ghai, Rajesh; Stroud, David A; Fairlie, David P; Suga, Hiroaki; Jackson, Lauren P; Teasdale, Rohan D; Passioura, Toby; Collins, Brett M

Chen, Kai-En; Guo, Qian; Hill, Timothy A; Cui, Yi; Kendall, Amy K; Yang, Zhe; Hall, Ryan J; Healy, Michael D; Sacharz, Joanna; Norwood, Suzanne J; Fonseka, Sachini; Xie, Boyang; Reid, Robert C; Leneva, Natalya; Parton, Robert G; Ghai, Rajesh; Stroud, David A; Fairlie, David P; Suga, Hiroaki; Jackson, Lauren P; Teasdale, Rohan D; Passioura, Toby; Collins, Brett M.

Afiliación

Chen KE; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Guo Q; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Hill TA; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Cui Y; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Kendall AK; School of Biomedical Sciences, The University of Queensland, St Lucia, Queensland 4072, Australia.
Yang Z; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA.
Hall RJ; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA.
Healy MD; School of Biomedical Sciences, The University of Queensland, St Lucia, Queensland 4072, Australia.
Sacharz J; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Norwood SJ; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Fonseka S; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3052, Australia.
Xie B; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Reid RC; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Leneva N; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA.
Parton RG; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA.
Ghai R; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Stroud DA; ARC Centre of Excellence for Innovations in Peptide and Protein Science, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Fairlie DP; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Suga H; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Jackson LP; Centre for Microscopy and Microanalysis, The University of Queensland, Queensland, Australia.
Teasdale RD; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.
Passioura T; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3052, Australia.
Collins BM; Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria 3052, Australia.

Sci Adv ; 7(49): eabg4007, 2021 Dec 03.

Article en En | MEDLINE | ID: mdl-34851660

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Sci Adv Año: 2021 Tipo del documento: Article País de afiliación: Australia