A Subset of Intracanalicular Vestibular Schwannomas Demonstrates Minimal Growth Over a 10-Year Period.
Otol Neurotol
; 43(3): 376-384, 2022 03 01.
Article
en En
| MEDLINE
| ID: mdl-35020686
ABSTRACT
OBJECTIVE:
Vestibular schwannomas (VS) commonly undergo magnetic resonance imaging (MRI) surveillance, but long-term data to support the ideal frequency is limited. Herein, we aim to investigate intracanalicular VS growth predictors and long-term growth rates (GR). STUDYDESIGN:
Retrospective chart review.SETTING:
Two tertiary care centers. PATIENTS Sporadic intracanalicular VS with initial conservative management and at least two sequential MRIs. INTERVENTION Serial MRI. MAIN OUTCOMEMEASURES:
VS were categorized by baseline internal auditory canal tertile sublocalization (fundus, midpoint, porus) and size (≤100, 100-200, >200âmm3). Throughout follow-up, volumetric GR (mm3/yr) were determined (baseline-3âyrs, 3-5âyrs, 5-10âyrs) and treatment rates were assessed.RESULTS:
Ninety-nine intracanalicular VS were identified (mean follow-up of 6.1â±â4.5âyrs). Mean GR before 5-year follow-up were comparable for baseline tertile involvement and size. After 5-year follow-up, mean GR of VS involving the fundus at baseline were lower than those involving the midpoint and fundus (6.17â±â21.16 and 119.74â±â117.57âmm3/yr, respectively; pâ=â0.034). Mean GR of VS with less than or equal to 100âmm3 at baseline (-7.29â±â25.44âmm3/yr) were lower than those with 100 to 200âmm3 (86.55â±â103.99âmm3/yr; pâ=â0.011) and more than 200âmm3 (45.70â±â35.71âmm3/yr; pâ=â0.031). Vestibular schwannomas involving the midpoint and fundus had greater treatment rates compared with VS involving only the fundus (pâ<â0.001).CONCLUSIONS:
Baseline tertile involvement and size may predict long-term intracanalicular VS growth where fundal tumors or those less than or equal to 100âmm3 exhibit little long-term growth. Extending surveillance after 5-year follow-up may be reasonable for fundal VS.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neuroma Acústico
/
Oído Interno
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Otol Neurotol
Asunto de la revista:
NEUROLOGIA
/
OTORRINOLARINGOLOGIA
Año:
2022
Tipo del documento:
Article