Green tea-derived theabrownin induces cellular senescence and apoptosis of hepatocellular carcinoma through p53 signaling activation and bypassed JNK signaling suppression.

Xu, Jiaan; Xiao, Xiujuan; Yan, Bo; Yuan, Qiang; Dong, Xiaoqiao; Du, Quan; Zhang, Jin; Shan, Letian; Ding, Zhishan; Zhou, Li; Efferth, Thomas

Xu, Jiaan; Xiao, Xiujuan; Yan, Bo; Yuan, Qiang; Dong, Xiaoqiao; Du, Quan; Zhang, Jin; Shan, Letian; Ding, Zhishan; Zhou, Li; Efferth, Thomas.

Afiliación

Xu J; College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Xiao X; The First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Yan B; College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Yuan Q; The First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Dong X; College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Du Q; The First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Zhang J; College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Shan L; Department of Neurosurgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Ding Z; Department of Neurosurgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Zhou L; Theabio Co., Ltd, Hangzhou, 310000, China.
Efferth T; The First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, 310053, China. letian.shan@zcmu.edu.cn.

Cancer Cell Int ; 22(1): 39, 2022 Jan 25.

Article en En | MEDLINE | ID: mdl-35078476

Palabras clave

Apoptosis; Cellular senescence; Hepatocellular carcinoma; JNK; SK-Hep-1; Theabrownin; p53

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Cancer Cell Int Año: 2022 Tipo del documento: Article País de afiliación: China