The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis.

Zhu, Youming; Jin, Lei; Shi, Ronghua; Li, Jinming; Wang, Yan; Zhang, Li; Liang, Chao-Zhao; Narayana, Vinod K; De Souza, David P; Thorne, Rick F; Zhang, Li Rong; Zhang, Xu Dong; Wu, Mian

Zhu, Youming; Jin, Lei; Shi, Ronghua; Li, Jinming; Wang, Yan; Zhang, Li; Liang, Chao-Zhao; Narayana, Vinod K; De Souza, David P; Thorne, Rick F; Zhang, Li Rong; Zhang, Xu Dong; Wu, Mian.

Afiliación

Zhu Y; Translational Research Institute, Henan Provincial People's Hospital, Academy of Medical Science, State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou University, Zhengzhou 450003, China; Department of Dental Implant Center, Stomatologic Hospital and College, Anhui Medical U
Jin L; Translational Research Institute, Henan Provincial People's Hospital, Academy of Medical Science, State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou University, Zhengzhou 450003, China; School of Medicine and Public Health, The University of Newcastle, Newcastle, NSW 2308,
Shi R; The Chinese Academy of Sciences (CAS) Key Laboratory of Innate Immunity and Chronic Disease, CAS Center for Excellence in Cell and Molecular Biology, School of Life Sciences, University of Science and Technology of China, Hefei 230026, China.
Li J; Translational Research Institute, Henan Provincial People's Hospital, Academy of Medical Science, State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou University, Zhengzhou 450003, China.
Wang Y; Translational Research Institute, Henan Provincial People's Hospital, Academy of Medical Science, State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou University, Zhengzhou 450003, China.
Zhang L; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei 230031, China.
Liang CZ; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei 230031, China.
Narayana VK; Bio21 Institute and Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, VIC 3010, Australia; Metabolomics Australia, University of Melbourne, Parkville, VIC 3010, Australia.
De Souza DP; Bio21 Institute and Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, VIC 3010, Australia; Metabolomics Australia, University of Melbourne, Parkville, VIC 3010, Australia.
Thorne RF; Translational Research Institute, Henan Provincial People's Hospital, Academy of Medical Science, State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou University, Zhengzhou 450003, China; School of Environmental and Life Sciences, The University of Newcastle, Newcastle, NSW
Zhang LR; Translational Research Institute, Henan Provincial People's Hospital, Academy of Medical Science, State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou University, Zhengzhou 450003, China. Electronic address: lrzhang@zzu.edu.cn.
Zhang XD; Translational Research Institute, Henan Provincial People's Hospital, Academy of Medical Science, State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou University, Zhengzhou 450003, China; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW
Wu M; Translational Research Institute, Henan Provincial People's Hospital, Academy of Medical Science, State Key Laboratory of Esophageal Cancer Prevention and Treatment, Zhengzhou University, Zhengzhou 450003, China; The Chinese Academy of Sciences (CAS) Key Laboratory of Innate Immunity and Chronic Dis

Mol Cell ; 82(3): 542-554.e6, 2022 02 03.

Article en En | MEDLINE | ID: mdl-35081364

Asunto(s)

Biomarcadores de Tumor/metabolismo; Proteínas Portadoras/metabolismo; Proteínas de Unión al ADN/metabolismo; Glucólisis; Proteínas de la Membrana/metabolismo; Neoplasias/enzimología; Fosfoglicerato Quinasa/metabolismo; Fosfoglicerato Mutasa/metabolismo; Fosfopiruvato Hidratasa/metabolismo; ARN Largo no Codificante/metabolismo; Hormonas Tiroideas/metabolismo; Proteínas Supresoras de Tumor/metabolismo; Adenosina Trifosfato/metabolismo; Animales; Biomarcadores de Tumor/genética; Proteínas Portadoras/genética; Proliferación Celular; Proteínas de Unión al ADN/genética; Femenino; Regulación Enzimológica de la Expresión Génica; Regulación Neoplásica de la Expresión Génica; Células HEK293; Células HeLa; Células Hep G2; Humanos; L-Lactato Deshidrogenasa/genética; L-Lactato Deshidrogenasa/metabolismo; Proteínas de la Membrana/genética; Ratones Desnudos; Complejos Multienzimáticos; Neoplasias/genética; Neoplasias/patología; Fosfoglicerato Quinasa/genética; Fosfoglicerato Mutasa/genética; Fosfopiruvato Hidratasa/genética; Proteínas Proto-Oncogénicas c-myc/genética; Proteínas Proto-Oncogénicas c-myc/metabolismo; ARN Largo no Codificante/genética; Serina/deficiencia; Hormonas Tiroideas/genética; Carga Tumoral; Proteínas Supresoras de Tumor/genética; Proteínas de Unión a Hormona Tiroide

Palabras clave

c-Myc; glycoLINC; glycolytic complex; metabolon; serine starvation

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fosfoglicerato Quinasa / Fosfopiruvato Hidratasa / Hormonas Tiroideas / Proteínas Portadoras / Biomarcadores de Tumor / Fosfoglicerato Mutasa / Proteínas Supresoras de Tumor / Proteínas de Unión al ADN / ARN Largo no Codificante / Glucólisis Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google