LC-ESI-MS/MS Identification of Biologically Active Phenolics in Different Extracts of Alchemilla acutiloba Opiz.
Molecules
; 27(3)2022 Jan 18.
Article
en En
| MEDLINE
| ID: mdl-35163884
ABSTRACT
Liquid chromatography electrospray ionization tandem mass spectrometric (LC-ESI-MS/MS) qualitative and quantitative analysis of different extracts from the aerial parts and roots of Alchemilla acutiloba led to the identification of phenolic acids and flavonoids. To the best of our knowledge, isorhamnetin 3-glucoside, kaempferol 3-rutinoside, narcissoside, naringenin 7-glucoside, 3-O-methylquercetin, naringenin, eriodictyol, rhamnetin, and isorhamnetin were described for the first time in Alchemilla genus. In addition, the antioxidant, anti-inflammatory and cytotoxic activity of all extracts were evaluated. The results clearly showed that among analyzed extracts, the butanol extract of the aerial parts exhibited the highest biological activity comparable with the positive controls used.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Fenoles
/
Flavonoides
/
Extractos Vegetales
/
Citotoxinas
/
Alchemilla
/
Antiinflamatorios
/
Antioxidantes
Tipo de estudio:
Diagnostic_studies
/
Qualitative_research
Límite:
Animals
Idioma:
En
Revista:
Molecules
Asunto de la revista:
BIOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Polonia