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In silico proof of principle of machine learning-based antibody design at unconstrained scale.
Akbar, Rahmad; Robert, Philippe A; Weber, Cédric R; Widrich, Michael; Frank, Robert; Pavlovic, Milena; Scheffer, Lonneke; Chernigovskaya, Maria; Snapkov, Igor; Slabodkin, Andrei; Mehta, Brij Bhushan; Miho, Enkelejda; Lund-Johansen, Fridtjof; Andersen, Jan Terje; Hochreiter, Sepp; Hobæk Haff, Ingrid; Klambauer, Günter; Sandve, Geir Kjetil; Greiff, Victor.
Afiliación
  • Akbar R; Department of Immunology, Oslo University Hospital Rikshospitalet and University of Oslo, Norway.
  • Robert PA; Department of Immunology, Oslo University Hospital Rikshospitalet and University of Oslo, Norway.
  • Weber CR; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.
  • Widrich M; Ellis Unit Linz and Lit Ai Lab, Institute for Machine Learning, Johannes Kepler University Linz, Linz, Austria.
  • Frank R; Department of Immunology, Oslo University Hospital Rikshospitalet and University of Oslo, Norway.
  • Pavlovic M; Department of Informatics, University of Oslo, Oslo, Norway.
  • Scheffer L; Department of Informatics, University of Oslo, Oslo, Norway.
  • Chernigovskaya M; Department of Immunology, Oslo University Hospital Rikshospitalet and University of Oslo, Norway.
  • Snapkov I; Department of Immunology, Oslo University Hospital Rikshospitalet and University of Oslo, Norway.
  • Slabodkin A; Department of Immunology, Oslo University Hospital Rikshospitalet and University of Oslo, Norway.
  • Mehta BB; Department of Immunology, Oslo University Hospital Rikshospitalet and University of Oslo, Norway.
  • Miho E; Institute of Medical Engineering and Medical Informatics, School of Life Sciences, FHNW University of Applied Sciences and Arts Northwestern Switzerland, Muttenz, Switzerland.
  • Lund-Johansen F; Department of Immunology, Oslo University Hospital Rikshospitalet and University of Oslo, Norway.
  • Andersen JT; Department of Immunology, Oslo University Hospital Rikshospitalet and University of Oslo, Norway.
  • Hochreiter S; Institute of Clinical Medicine, Department of Pharmacology, University of Oslo, Oslo, Norway.
  • Hobæk Haff I; Ellis Unit Linz and Lit Ai Lab, Institute for Machine Learning, Johannes Kepler University Linz, Linz, Austria.
  • Klambauer G; Institute of Advanced Research in Artificial Intelligence (IARAI), Austria.
  • Sandve GK; Department of Mathematics, University of Oslo, Oslo, Norway.
  • Greiff V; Ellis Unit Linz and Lit Ai Lab, Institute for Machine Learning, Johannes Kepler University Linz, Linz, Austria.
MAbs ; 14(1): 2031482, 2022.
Article en En | MEDLINE | ID: mdl-35377271

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Aprendizaje Automático / Reacciones Antígeno-Anticuerpo Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Noruega

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Aprendizaje Automático / Reacciones Antígeno-Anticuerpo Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Noruega