Sirt3 Pharmacologically Promotes Insulin Sensitivity through PI3/AKT/mTOR and Their Downstream Pathway in Adipocytes.

Lee, Alexandra Yatine; Christensen, Sabrina Marie; Duong, Nhi; Tran, Quoc-Anh; Xiong, Hou Mai; Huang, Jennifer; James, Sarah; Vallabh, Dimple; Talbott, George; Rose, Melanie; Ho, Linh

Lee, Alexandra Yatine; Christensen, Sabrina Marie; Duong, Nhi; Tran, Quoc-Anh; Xiong, Hou Mai; Huang, Jennifer; James, Sarah; Vallabh, Dimple; Talbott, George; Rose, Melanie; Ho, Linh.

Afiliación

Lee AY; College of Medicine, California Northstate University, Elk Grove, CA 95757, USA.
Christensen SM; College of Medicine, California Northstate University, Elk Grove, CA 95757, USA.
Duong N; College of Pharmacy, California Northstate University, Elk Grove, CA 95757, USA.
Tran QA; College of Pharmacy, California Northstate University, Elk Grove, CA 95757, USA.
Xiong HM; College of Pharmacy, California Northstate University, Elk Grove, CA 95757, USA.
Huang J; College of Pharmacy, California Northstate University, Elk Grove, CA 95757, USA.
James S; College of Pharmacy, California Northstate University, Elk Grove, CA 95757, USA.
Vallabh D; College of Pharmacy, California Northstate University, Elk Grove, CA 95757, USA.
Talbott G; College of Pharmacy, California Northstate University, Elk Grove, CA 95757, USA.
Rose M; College of Pharmacy, California Northstate University, Elk Grove, CA 95757, USA.
Ho L; College of Pharmacy, California Northstate University, Elk Grove, CA 95757, USA.

Int J Mol Sci ; 23(7)2022 Mar 29.

Article en En | MEDLINE | ID: mdl-35409099

Asunto(s)

Diabetes Mellitus Tipo 2; Resistencia a la Insulina; Sirtuina 3; Adipocitos/metabolismo; Citocinas/metabolismo; Diabetes Mellitus Tipo 2/metabolismo; Ácidos Grasos no Esterificados/metabolismo; Glucosa/metabolismo; Glucógeno Sintasa Quinasa 3 beta/metabolismo; Humanos; Insulina/metabolismo; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Sirtuina 3/genética; Sirtuina 3/metabolismo; Serina-Treonina Quinasas TOR/metabolismo

Palabras clave

3-TYP; PI3K/AKT/mTOR signaling pathway; Sirt3; Sirt3 activator; Sirt3 inhibitor; adipocytes; honokiol; insulin pathway; insulin/IGF-1 (Insulin-like Growth Factor-1) signaling pathway; mitochondrial sirtuins

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Resistencia a la Insulina / Diabetes Mellitus Tipo 2 / Sirtuina 3 Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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