Somatic Mutations of Hematopoietic Cells Are an Additional Mechanism of Body Aging, Conducive to Comorbidity and Increasing Chronification of Inflammation.

Yegorov, Yegor E; Poznyak, Anastasia V; Bezsonov, Evgeny E; Zhuravlev, Alexander D; Nikiforov, Nikita G; Vishnyakova, Khava S; Orekhov, Alexander N

Yegorov, Yegor E; Poznyak, Anastasia V; Bezsonov, Evgeny E; Zhuravlev, Alexander D; Nikiforov, Nikita G; Vishnyakova, Khava S; Orekhov, Alexander N.

Afiliación

Yegorov YE; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Poznyak AV; Institute for Atherosclerosis Research, 121609 Moscow, Russia.
Bezsonov EE; Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Zhuravlev AD; Institute of Human Morphology, 117418 Moscow, Russia.
Nikiforov NG; Department of Biology and General Genetics, I.M. Sechenov First Moscow State Medical University (Sechenov University), 105043 Moscow, Russia.
Vishnyakova KS; Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Orekhov AN; Institute of Human Morphology, 117418 Moscow, Russia.

Biomedicines ; 10(4)2022 Mar 27.

Article en En | MEDLINE | ID: mdl-35453534

Palabras clave

CHIP; aging; bone marrow; chronification of inflammation; inflammation; mitochondria; monocytes; somatic mutations

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Biomedicines Año: 2022 Tipo del documento: Article País de afiliación: Rusia