Brain Cells Release Calreticulin That Attracts and Activates Microglia, and Inhibits Amyloid Beta Aggregation and Neurotoxicity.

Reid, Kyle M; Kitchener, Emily J A; Butler, Claire A; Cockram, Tom O J; Brown, Guy C

Reid, Kyle M; Kitchener, Emily J A; Butler, Claire A; Cockram, Tom O J; Brown, Guy C.

Afiliación

Reid KM; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Kitchener EJA; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Butler CA; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Cockram TOJ; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Brown GC; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.

Front Immunol ; 13: 859686, 2022.

Article en En | MEDLINE | ID: mdl-35514983

Asunto(s)

Péptidos beta-Amiloides; Síndromes de Neurotoxicidad; Péptidos beta-Amiloides/metabolismo; Encéfalo/metabolismo; Calreticulina/metabolismo; Células Cultivadas; Humanos; Microglía/metabolismo; Síndromes de Neurotoxicidad/metabolismo

Palabras clave

alarmin; amyloid beta; brain; calreticulin; chaperone; microglia; neurotoxicity

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Péptidos beta-Amiloides / Síndromes de Neurotoxicidad Límite: Humans Idioma: En Revista: Front Immunol Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

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