Frequency and therapeutic strategy for patients with ovarian metastasis from gastric cancer.
Langenbecks Arch Surg
; 407(6): 2301-2308, 2022 Sep.
Article
en En
| MEDLINE
| ID: mdl-35551466
ABSTRACT
PURPOSE:
This study aimed to analyze the clinicopathological features and treatment outcomes of ovarian metastasis from gastric cancer.METHODS:
This study included 155 female patients with unresectable advanced or recurrent gastric cancer at the Kochi Medical School between January 2007 and December 2021. A review of patients with ovarian metastasis was conducted, and their clinicopathological information and survival outcomes were compared with respect to ovarian metastasis.RESULTS:
Fifteen patients were diagnosed with ovarian metastasis from gastric cancer with a median age of 54 years (range 30-87 years) and an incidence of 9.7%. The median age of patients who developed ovarian metastasis was significantly lower those without ovarian metastasis (54 years vs. 71 years, P = 0.014). The median survival time (MST) for 15 patients with unresectable advanced gastric cancer who developed ovarian metastasis was 21.4 months (range 0.2-41.4 months). The MST for 15 patients who underwent surgical resection and systemic drug treatment including chemotherapy to ovarian metastasis was significantly higher than those who received systemic drug treatment alone (28.1 months vs. 10.0 months; P = 0.021).CONCLUSION:
Ovarian metastasis was found in 9.7% of female patients with unresectable advanced or recurrent gastric cancer and in younger patients than in those without ovarian metastasis. Multidisciplinary treatment, including surgical resection and systemic drug treatment for ovarian metastasis from gastric cancer, may benefit selected patients.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Ováricas
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Neoplasias Gástricas
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Tumor de Krukenberg
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
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Aged
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Aged80
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Female
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Humans
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Middle aged
Idioma:
En
Revista:
Langenbecks Arch Surg
Año:
2022
Tipo del documento:
Article
País de afiliación:
Japón