[Hepatic involvement in secondary syphilis]. / Atteinte hépatique au cours de la syphilis secondaire.
Gastroenterol Clin Biol
; 11(1): 93-5, 1987 Jan.
Article
en Fr
| MEDLINE
| ID: mdl-3556964
A case of secondary syphilitic hepatitis is reported. A 49-year old woman was admitted for weight-loss, fever, hepatomegaly and splenomegaly. Diagnosis of syphilitic hepatitis was based on cholestasis associated with positive serologic tests for syphilis without other immunological disturbances. Biopsy of the liver showed a moderate infiltration in and around the portal tracts. Immunofluorescence study for treponema was negative. Rapid improvement was obtained with penicillin initially associated with steroid therapy. Liver involvement in secondary syphilis is characterized by anicteric cholestasis, an inflammatory syndrome, and periportal infiltrate inconstantly associated with centrilobular necrosis, granulomatous reaction and presence of treponemas in the lesions. Due to the increasing frequency of sexually transmitted diseases, this diagnosis could become more frequent.
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Bases de datos:
MEDLINE
Asunto principal:
Sífilis
/
Hepatitis
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
Fr
Revista:
Gastroenterol Clin Biol
Año:
1987
Tipo del documento:
Article