Can We Treat Neurodegenerative Proteinopathies by Enhancing Protein Degradation?

Engelender, Simone; Stefanis, Leonidas; Oddo, Salvatore; Bellucci, Arianna

Engelender, Simone; Stefanis, Leonidas; Oddo, Salvatore; Bellucci, Arianna.

Afiliación

Engelender S; Department of Biochemistry, The B. Rappaport Faculty of Medicine and Institute of Medical Research, Technion-Israel Institute of Technology, Haifa, Israel.
Stefanis L; Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
Oddo S; First Department of Neurology, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Bellucci A; Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy.

Mov Disord ; 37(7): 1346-1359, 2022 07.

Article en En | MEDLINE | ID: mdl-35579450

Asunto(s)

Esclerosis Amiotrófica Lateral; Degeneración Lobar Frontotemporal; Humanos; Agregado de Proteínas; Proteínas/metabolismo; Proteolisis; Ubiquitina/metabolismo

Palabras clave

autophagy lysosomal pathway; neurodegenerative proteinopathies; pathological protein aggregates; therapeutic strategies; ubiquitin proteasomal system

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Degeneración Lobar Frontotemporal / Esclerosis Amiotrófica Lateral Límite: Humans Idioma: En Revista: Mov Disord Asunto de la revista: NEUROLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Israel

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google