Dynamic Visualization of TGF-ß/SMAD3 Transcriptional Responses in Single Living Cells.

Marvin, Dieuwke L; You, Li; Bornes, Laura; van Dinther, Maarten; Peters, Niek; Dang, Hao; Hakuno, Sarah K; Hornsveld, Marten; Kranenburg, Onno; van Rheenen, Jacco; Rohling, Jos H T; Chien, Miao-Ping; Ten Dijke, Peter; Ritsma, Laila

Marvin, Dieuwke L; You, Li; Bornes, Laura; van Dinther, Maarten; Peters, Niek; Dang, Hao; Hakuno, Sarah K; Hornsveld, Marten; Kranenburg, Onno; van Rheenen, Jacco; Rohling, Jos H T; Chien, Miao-Ping; Ten Dijke, Peter; Ritsma, Laila.

Afiliación

Marvin DL; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
You L; Oncode Institute and Department of Molecular Genetics, Erasmus University Medical Center, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.
Bornes L; Oncode Institute and Department of Molecular Pathology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
van Dinther M; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Peters N; UMC Utrecht Cancer Center, University Medical Center Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
Dang H; Department of Gastroenterology and Hepatology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Hakuno SK; Department of Gastroenterology and Hepatology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Hornsveld M; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Kranenburg O; Department of Gastroenterology and Hepatology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
van Rheenen J; UMC Utrecht Cancer Center, University Medical Center Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
Rohling JHT; Oncode Institute and Department of Molecular Pathology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Chien MP; Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Ten Dijke P; Oncode Institute and Department of Molecular Genetics, Erasmus University Medical Center, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.
Ritsma L; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.

Cancers (Basel) ; 14(10)2022 May 19.

Article en En | MEDLINE | ID: mdl-35626109

Palabras clave

TGF-ß signaling; signaling dynamics; signaling heterogeneity; transcriptional reporter

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Cancers (Basel) Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos