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An iodine-containing probe as a tool for molecular detection in secondary ion mass spectrometry.
Kabatas Glowacki, Selda; Agüi-Gonzalez, Paola; Sograte-Idrissi, Shama; Jähne, Sebastian; Opazo, Felipe; Phan, Nhu T N; Rizzoli, Silvio O.
Afiliación
  • Kabatas Glowacki S; Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, Von-Siebold-Straße 3a, 37075 Göttingen, Germany. srizzol@gwdg.de.
  • Agüi-Gonzalez P; Department of Neuro and Sensory Physiology, University Medical Center, Göttingen, Humboldtalee 23, 37073 Göttingen, Germany.
  • Sograte-Idrissi S; Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, Von-Siebold-Straße 3a, 37075 Göttingen, Germany. srizzol@gwdg.de.
  • Jähne S; Department of Neuro and Sensory Physiology, University Medical Center, Göttingen, Humboldtalee 23, 37073 Göttingen, Germany.
  • Opazo F; Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, Von-Siebold-Straße 3a, 37075 Göttingen, Germany. srizzol@gwdg.de.
  • Phan NTN; Department of Neuro and Sensory Physiology, University Medical Center, Göttingen, Humboldtalee 23, 37073 Göttingen, Germany.
  • Rizzoli SO; Department of Neuro and Sensory Physiology, University Medical Center, Göttingen, Humboldtalee 23, 37073 Göttingen, Germany.
Chem Commun (Camb) ; 58(54): 7558-7561, 2022 Jul 05.
Article en En | MEDLINE | ID: mdl-35708485
ABSTRACT
We developed here an iodine-containing probe that can be used to identify the molecules of interest in secondary ion mass spectrometry (SIMS) by simple immunolabelling procedures. The immunolabelled iodine probe was readily combined with previously-developed SIMS probes carrying fluorine, to generate dual-channel SIMS data. This probe should provide a useful complement to the currently available SIMS probes, thus expanding the scope of this technology.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Espectrometría de Masa de Ion Secundario / Yodo Tipo de estudio: Diagnostic_studies Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Espectrometría de Masa de Ion Secundario / Yodo Tipo de estudio: Diagnostic_studies Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Alemania