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Safety and immunogenicity of the inactivated whole-virus adjuvanted COVID-19 vaccine VLA2001: A randomized, dose escalation, double-blind phase 1/2 clinical trial in healthy adults.
Lazarus, Rajeka; Taucher, Christian; Brown, Claire; Corbic Ramljak, Irena; Danon, Leon; Dubischar, Katrin; Duncan, Christopher J A; Eder-Lingelbach, Susanne; Faust, Saul N; Green, Christopher; Gokani, Karishma; Hochreiter, Romana; Wright, Johanna Kellett; Kwon, Dowan; Middleditch, Alexander; Munro, Alasdair P S; Naker, Kush; Penciu, Florentina; Price, David; Querton, Benedicte; Riaz, Tawassal; Ross-Russell, Amy; Sanchez-Gonzalez, Amada; Wardle, Hayley; Warren, Sarah; Finn, Adam.
Afiliación
  • Lazarus R; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
  • Taucher C; Valneva Austria GmbH, Campus Vienna Biocenter 3, Vienna 1030, Austria. Electronic address: christian.taucher@valneva.com.
  • Brown C; NIHR/Wellcome Trust Clinical Research Facility, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
  • Corbic Ramljak I; Valneva Austria GmbH, Campus Vienna Biocenter 3, Vienna 1030, Austria.
  • Danon L; Department of Engineering Mathematics, University of Bristol, Bristol, UK.
  • Dubischar K; Valneva Austria GmbH, Campus Vienna Biocenter 3, Vienna 1030, Austria.
  • Duncan CJA; Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Translational and Clinical Research Institute, Immunity and Inflammation Theme, Newcastle, UK.
  • Eder-Lingelbach S; Valneva Austria GmbH, Campus Vienna Biocenter 3, Vienna 1030, Austria.
  • Faust SN; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK.
  • Green C; NIHR/Wellcome Trust Clinical Research Facility, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
  • Gokani K; NIHR/Wellcome Trust Clinical Research Facility, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
  • Hochreiter R; Valneva Austria GmbH, Campus Vienna Biocenter 3, Vienna 1030, Austria.
  • Wright JK; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
  • Kwon D; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
  • Middleditch A; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
  • Munro APS; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK.
  • Naker K; NIHR/Wellcome Trust Clinical Research Facility, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
  • Penciu F; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
  • Price D; Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Translational and Clinical Research Institute, Immunity and Inflammation Theme, Newcastle, UK.
  • Querton B; Valneva Austria GmbH, Campus Vienna Biocenter 3, Vienna 1030, Austria.
  • Riaz T; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
  • Ross-Russell A; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK.
  • Sanchez-Gonzalez A; Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Translational and Clinical Research Institute, Immunity and Inflammation Theme, Newcastle, UK.
  • Wardle H; Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Translational and Clinical Research Institute, Immunity and Inflammation Theme, Newcastle, UK.
  • Warren S; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK.
  • Finn A; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK; Schools of Population Health Sciences and Cellular and Molecular Medicine, University of Bristol, Bristol, UK.
J Infect ; 85(3): 306-317, 2022 09.
Article en En | MEDLINE | ID: mdl-35718205
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Vacunas contra la COVID-19 / COVID-19 Tipo de estudio: Clinical_trials Límite: Adult / Humans Idioma: En Revista: J Infect Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Vacunas contra la COVID-19 / COVID-19 Tipo de estudio: Clinical_trials Límite: Adult / Humans Idioma: En Revista: J Infect Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido