Musculoskeletal Deficits and Cognitive Impairment: Epidemiological Evidence and Biological Mechanisms.
Curr Osteoporos Rep
; 20(5): 260-272, 2022 10.
Article
en En
| MEDLINE
| ID: mdl-35764750
ABSTRACT
PURPOSE OF REVIEW Cognitive impairment is associated with obesity, sarcopenia, and osteoporosis. However, no critical appraisal of the literature on the relationship between musculoskeletal deficits and cognitive impairment, focusing on the epidemiological evidence and biological mechanisms, has been published to date. Herein, we critically evaluate the literature published over the past 3 years, emphasizing interesting and important new findings, and provide an outline of future directions that will improve our understanding of the connections between the brain and the musculoskeletal system. RECENT FINDINGS:
Recent literature suggests that musculoskeletal deficits and cognitive impairment share pathophysiological pathways and risk factors. Cytokines and hormones affect both the brain and the musculoskeletal system; yet, lack of unified definitions and standards makes it difficult to compare studies. Interventions designed to improve musculoskeletal health are plausible means of preventing or slowing cognitive impairment. We highlight several musculoskeletal health interventions that show potential in this regard.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Sarcopenia
/
Disfunción Cognitiva
/
Sistema Musculoesquelético
Tipo de estudio:
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Curr Osteoporos Rep
Asunto de la revista:
ORTOPEDIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Australia