3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death.

Pacchiana, Raffaella; Mullappilly, Nidula; Pinto, Andrea; Bova, Stefania; Forciniti, Stefania; Cullia, Gregorio; Dalla Pozza, Elisa; Bottani, Emanuela; Decimo, Ilaria; Dando, Ilaria; Bruno, Stefano; Conti, Paola; Donadelli, Massimo

Pacchiana, Raffaella; Mullappilly, Nidula; Pinto, Andrea; Bova, Stefania; Forciniti, Stefania; Cullia, Gregorio; Dalla Pozza, Elisa; Bottani, Emanuela; Decimo, Ilaria; Dando, Ilaria; Bruno, Stefano; Conti, Paola; Donadelli, Massimo.

Afiliación

Pacchiana R; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37134 Verona, Italy.
Mullappilly N; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37134 Verona, Italy.
Pinto A; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, 20133 Milan, Italy.
Bova S; Department of Medicine and Surgery, University of Parma, 43121 Parma, Italy.
Forciniti S; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37134 Verona, Italy.
Cullia G; Department of Pharmaceutical Sciences, University of Milan, 20133 Milano, Italy.
Dalla Pozza E; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37134 Verona, Italy.
Bottani E; Department of Diagnostic and Public Health, Section of Pharmacology, University of Verona, 37134 Verona, Italy.
Decimo I; Department of Diagnostic and Public Health, Section of Pharmacology, University of Verona, 37134 Verona, Italy.
Dando I; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37134 Verona, Italy.
Bruno S; Food and Drug Department, University of Parma, 43124 Parma, Italy.
Conti P; Department of Pharmaceutical Sciences, University of Milan, 20133 Milano, Italy.
Donadelli M; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37134 Verona, Italy.

Cancers (Basel) ; 14(13)2022 Jun 27.

Article en En | MEDLINE | ID: mdl-35804925

Palabras clave

GAPDH; apoptosis; autophagy; cancer metabolism; cell death; pancreas cancer

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Cancers (Basel) Año: 2022 Tipo del documento: Article País de afiliación: Italia