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Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses.
Yan, Juan; Chen, Yuedan; Patel, Amish J; Warda, Sarah; Lee, Cindy J; Nixon, Briana G; Wong, Elissa Wp; Miranda-Román, Miguel A; Yang, Ning; Wang, Yi; Pachai, Mohini R; Sher, Jessica; Giff, Emily; Tang, Fanying; Khurana, Ekta; Singer, Sam; Liu, Yang; Galbo, Phillip M; Maag, Jesper Lv; Koche, Richard P; Zheng, Deyou; Antonescu, Cristina R; Deng, Liang; Li, Ming O; Chen, Yu; Chi, Ping.
Afiliación
  • Yan J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering (MSK) Cancer Center, New York, New York, USA.
  • Chen Y; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering (MSK) Cancer Center, New York, New York, USA.
  • Patel AJ; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York, USA.
  • Warda S; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering (MSK) Cancer Center, New York, New York, USA.
  • Lee CJ; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering (MSK) Cancer Center, New York, New York, USA.
  • Nixon BG; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering (MSK) Cancer Center, New York, New York, USA.
  • Wong EW; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York, USA.
  • Miranda-Román MA; Immunology Program, Sloan Kettering Institute.
  • Yang N; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering (MSK) Cancer Center, New York, New York, USA.
  • Wang Y; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering (MSK) Cancer Center, New York, New York, USA.
  • Pachai MR; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, and.
  • Sher J; Dermatology Service, Department of Medicine, MSK Cancer Center, New York, New York, USA.
  • Giff E; Dermatology Service, Department of Medicine, MSK Cancer Center, New York, New York, USA.
  • Tang F; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering (MSK) Cancer Center, New York, New York, USA.
  • Khurana E; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering (MSK) Cancer Center, New York, New York, USA.
  • Singer S; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering (MSK) Cancer Center, New York, New York, USA.
  • Liu Y; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York, USA.
  • Galbo PM; Institute for Computational Biomedicine.
  • Maag JL; Meyer Cancer Center, and.
  • Koche RP; Institute for Computational Biomedicine.
  • Zheng D; Meyer Cancer Center, and.
  • Antonescu CR; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York, USA.
  • Deng L; Department of Surgery, MSK Cancer Center, New York, New York, USA.
  • Li MO; Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Chen Y; Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Chi P; Center for Epigenetics Research, MSK Cancer Center, New York, New York, USA.
J Clin Invest ; 132(17)2022 09 01.
Article en En | MEDLINE | ID: mdl-35852856

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Virus / Neoplasias Límite: Humans Idioma: En Revista: J Clin Invest Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Virus / Neoplasias Límite: Humans Idioma: En Revista: J Clin Invest Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos