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Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration.
Gomez-Sintes, Raquel; Xin, Qisheng; Jimenez-Loygorri, Juan Ignacio; McCabe, Mericka; Diaz, Antonio; Garner, Thomas P; Cotto-Rios, Xiomaris M; Wu, Yang; Dong, Shuxian; Reynolds, Cara A; Patel, Bindi; de la Villa, Pedro; Macian, Fernando; Boya, Patricia; Gavathiotis, Evripidis; Cuervo, Ana Maria.
Afiliación
  • Gomez-Sintes R; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Xin Q; Institute for Aging Studies of the Department of Medicine of the Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Jimenez-Loygorri JI; Department of Cellular and Molecular Biology, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, 28040, Spain.
  • McCabe M; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Diaz A; Institute for Aging Studies of the Department of Medicine of the Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Garner TP; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Cotto-Rios XM; Department of Cellular and Molecular Biology, Centro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, 28040, Spain.
  • Wu Y; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Dong S; Institute for Aging Studies of the Department of Medicine of the Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Reynolds CA; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Patel B; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • de la Villa P; Institute for Aging Studies of the Department of Medicine of the Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Macian F; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Boya P; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Gavathiotis E; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Cuervo AM; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Nat Commun ; 13(1): 4220, 2022 07 21.
Article en En | MEDLINE | ID: mdl-35864098
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Degeneración Retiniana / Retinitis Pigmentosa / Autofagia Mediada por Chaperones Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Degeneración Retiniana / Retinitis Pigmentosa / Autofagia Mediada por Chaperones Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos