Pretreatment of nucleus pulposus mesenchymal stem cells with appropriate concentration of H<sub>2</sub>O<sub>2</sub> enhances their ability to treat intervertebral disc degeneration.

Zhang, Yu-Yao; Hu, Zhi-Lei; Qi, Yu-Han; Li, Hai-Yin; Chang, Xian; Gao, Xiao-Xin; Liu, Chen-Hao; Li, Yue-Yang; Lou, Jin-Hui; Zhai, Yu; Li, Chang-Qing

Pretreatment of nucleus pulposus mesenchymal stem cells with appropriate concentration of H₂O₂ enhances their ability to treat intervertebral disc degeneration.

Zhang, Yu-Yao; Hu, Zhi-Lei; Qi, Yu-Han; Li, Hai-Yin; Chang, Xian; Gao, Xiao-Xin; Liu, Chen-Hao; Li, Yue-Yang; Lou, Jin-Hui; Zhai, Yu; Li, Chang-Qing.

Afiliación

Zhang YY; Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing, 400037, China.
Hu ZL; Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing, 400037, China.
Qi YH; Institute of Basic Theory of Traditional Chinese Medicine, China Academy of Chinese Medical Science, Beijing, 100000, China.
Li HY; Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing, 400037, China.
Chang X; Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing, 400037, China.
Gao XX; Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing, 400037, China.
Liu CH; Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing, 400037, China.
Li YY; Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing, 400037, China.
Lou JH; Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing, 400037, China.
Zhai Y; Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing, 400037, China. zhaiyu9501@163.com.
Li CQ; Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing, 400037, China. changqli1970@126.com.

Stem Cell Res Ther ; 13(1): 340, 2022 07 26.

Article en En | MEDLINE | ID: mdl-35883157

Asunto(s)

Degeneración del Disco Intervertebral; Disco Intervertebral; Células Madre Mesenquimatosas; Núcleo Pulposo; Animales; Apoptosis; Peróxido de Hidrógeno/farmacología; Disco Intervertebral/patología; Degeneración del Disco Intervertebral/patología; Proteína 1 Asociada A ECH Tipo Kelch; Células Madre Mesenquimatosas/metabolismo; Factor 2 Relacionado con NF-E2/genética; Factor 2 Relacionado con NF-E2/metabolismo; Proteínas Nucleares/metabolismo; Núcleo Pulposo/metabolismo; Ratas

Palabras clave

H2O2; IVDD; NPMSCs; Pretreatment; Transplantation

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Degeneración del Disco Intervertebral / Células Madre Mesenquimatosas / Núcleo Pulposo / Disco Intervertebral Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Stem Cell Res Ther Año: 2022 Tipo del documento: Article País de afiliación: China

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