Heparin promotes rapid fibrillation of the basic parathyroid hormone at physiological pH.

Lauth, Luca M; Voigt, Bruno; Bhatia, Twinkle; Machner, Lisa; Balbach, Jochen; Ott, Maria

Lauth, Luca M; Voigt, Bruno; Bhatia, Twinkle; Machner, Lisa; Balbach, Jochen; Ott, Maria.

Afiliación

Lauth LM; Department of Biochemistry and Biotechnology, Martin-Luther-University Halle-Wittenberg, Germany.
Voigt B; Department of Biophysics, Martin-Luther-University Halle-Wittenberg, Germany.
Bhatia T; Department of Biochemistry and Biotechnology, Martin-Luther-University Halle-Wittenberg, Germany.
Machner L; Department of Molecular Medicine, Martin-Luther-University Halle-Wittenberg, Germany.
Balbach J; Department of Biophysics, Martin-Luther-University Halle-Wittenberg, Germany.
Ott M; Department of Biophysics, Martin-Luther-University Halle-Wittenberg, Germany.

FEBS Lett ; 596(22): 2928-2939, 2022 11.

Article en En | MEDLINE | ID: mdl-35903816

Asunto(s)

Amiloide; Heparina; Animales; Heparina/metabolismo; Amiloide/metabolismo; Hormona Paratiroidea/química; Hormona Paratiroidea/metabolismo; Dispersión del Ángulo Pequeño; Difracción de Rayos X; Concentración de Iones de Hidrógeno; Mamíferos

Palabras clave

acidic pH; amyloid fibrillation; functional amyloids; heparin interaction; intrinsically disordered proteins; parathyroid hormone

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Heparina / Amiloide Límite: Animals Idioma: En Revista: FEBS Lett Año: 2022 Tipo del documento: Article País de afiliación: Alemania

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