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DOCK2 is involved in the host genetics and biology of severe COVID-19.
Namkoong, Ho; Edahiro, Ryuya; Takano, Tomomi; Nishihara, Hiroshi; Shirai, Yuya; Sonehara, Kyuto; Tanaka, Hiromu; Azekawa, Shuhei; Mikami, Yohei; Lee, Ho; Hasegawa, Takanori; Okudela, Koji; Okuzaki, Daisuke; Motooka, Daisuke; Kanai, Masahiro; Naito, Tatsuhiko; Yamamoto, Kenichi; Wang, Qingbo S; Saiki, Ryunosuke; Ishihara, Rino; Matsubara, Yuta; Hamamoto, Junko; Hayashi, Hiroyuki; Yoshimura, Yukihiro; Tachikawa, Natsuo; Yanagita, Emmy; Hyugaji, Takayoshi; Shimizu, Eigo; Katayama, Kotoe; Kato, Yasuhiro; Morita, Takayoshi; Takahashi, Kazuhisa; Harada, Norihiro; Naito, Toshio; Hiki, Makoto; Matsushita, Yasushi; Takagi, Haruhi; Aoki, Ryousuke; Nakamura, Ai; Harada, Sonoko; Sasano, Hitoshi; Kabata, Hiroki; Masaki, Katsunori; Kamata, Hirofumi; Ikemura, Shinnosuke; Chubachi, Shotaro; Okamori, Satoshi; Terai, Hideki; Morita, Atsuho; Asakura, Takanori.
Afiliación
  • Namkoong H; Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan.
  • Edahiro R; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Takano T; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Nishihara H; Laboratory of Veterinary Infectious Disease, School of Veterinary Medicine, Kitasato University, Aomori, Japan.
  • Shirai Y; Genomics Unit, Keio Cancer Center, Keio University Hospital, Tokyo, Japan.
  • Sonehara K; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Tanaka H; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Azekawa S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Mikami Y; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Japan.
  • Lee H; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Hasegawa T; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Okudela K; Division of Gastroenterology and Hepatology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Okuzaki D; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Motooka D; M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan.
  • Kanai M; Department of Pathology, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
  • Naito T; Single Cell Genomics, Human Immunology, WPI Immunology Frontier Research Center, Osaka University, Suita, Japan.
  • Yamamoto K; Genome Information Research Center, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
  • Wang QS; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Saiki R; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Ishihara R; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Matsubara Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Hamamoto J; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.
  • Hayashi H; Division of Gastroenterology and Hepatology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Yoshimura Y; Division of Gastroenterology and Hepatology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Tachikawa N; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Yanagita E; Division of Pathology, Yokohama Municipal Citizen's Hospital, Yokohama, Japan.
  • Hyugaji T; Division of Infectious Disease, Yokohama Municipal Citizen's Hospital, Yokohama, Japan.
  • Shimizu E; Division of Infectious Disease, Yokohama Municipal Citizen's Hospital, Yokohama, Japan.
  • Katayama K; Genomics Unit, Keio Cancer Center, Keio University Hospital, Tokyo, Japan.
  • Kato Y; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
  • Morita T; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
  • Takahashi K; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
  • Harada N; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Naito T; Department of Immunopathology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan.
  • Hiki M; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Matsushita Y; Department of Immunopathology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan.
  • Takagi H; Department of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan.
  • Aoki R; Department of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan.
  • Nakamura A; Department of General Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan.
  • Harada S; Department of Emergency and Disaster Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan.
  • Sasano H; Department of Cardiovascular Biology and Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan.
  • Kabata H; Department of Internal Medicine and Rheumatology, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan.
  • Masaki K; Department of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan.
  • Kamata H; Department of Nephrology, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan.
  • Ikemura S; Department of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan.
  • Chubachi S; Department of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan.
  • Okamori S; Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
  • Terai H; Department of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan.
  • Morita A; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Asakura T; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Nature ; 609(7928): 754-760, 2022 09.
Article en En | MEDLINE | ID: mdl-35940203
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Activadoras de GTPasa / Factores de Intercambio de Guanina Nucleótido / Estudio de Asociación del Genoma Completo / Interacciones Microbiota-Huesped / SARS-CoV-2 / COVID-19 Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Middle aged País/Región como asunto: Asia Idioma: En Revista: Nature Año: 2022 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Activadoras de GTPasa / Factores de Intercambio de Guanina Nucleótido / Estudio de Asociación del Genoma Completo / Interacciones Microbiota-Huesped / SARS-CoV-2 / COVID-19 Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Middle aged País/Región como asunto: Asia Idioma: En Revista: Nature Año: 2022 Tipo del documento: Article País de afiliación: Japón