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Epigenetic Regulation of Optic Nerve Development, Protection, and Repair.
Ashok, Ajay; Pooranawattanakul, Sarita; Tai, Wai Lydia; Cho, Kin-Sang; Utheim, Tor P; Cestari, Dean M; Chen, Dong Feng.
Afiliación
  • Ashok A; Department of Ophthalmology, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.
  • Pooranawattanakul S; Department of Ophthalmology, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.
  • Tai WL; Department of Ophthalmology, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.
  • Cho KS; Department of Ophthalmology, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.
  • Utheim TP; Department of Medical Biochemistry, Oslo University Hospital, 0372 Oslo, Norway.
  • Cestari DM; Department of Ophthalmology, Oslo University Hospital, 0372 Oslo, Norway.
  • Chen DF; Department of Ophthalmology, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.
Int J Mol Sci ; 23(16)2022 Aug 10.
Article en En | MEDLINE | ID: mdl-36012190
ABSTRACT
Epigenetic factors are known to influence tissue development, functionality, and their response to pathophysiology. This review will focus on different types of epigenetic regulators and their associated molecular apparatus that affect the optic nerve. A comprehensive understanding of epigenetic regulation in optic nerve development and homeostasis will help us unravel novel molecular pathways and pave the way to design blueprints for effective therapeutics to address optic nerve protection, repair, and regeneration.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oligodendroglía / Vaina de Mielina Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oligodendroglía / Vaina de Mielina Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos