Memo1 binds reduced copper ions, interacts with copper chaperone Atox1, and protects against copper-mediated redox activity in vitro.

Zhang, Xiaolu; Walke, Gulshan R; Horvath, Istvan; Kumar, Ranjeet; Blockhuys, Stéphanie; Holgersson, Stellan; Walton, Paul H; Wittung-Stafshede, Pernilla

Memo1 binds reduced copper ions, interacts with copper chaperone Atox1, and protects against copper-mediated redox activity in vitro.

Zhang, Xiaolu; Walke, Gulshan R; Horvath, Istvan; Kumar, Ranjeet; Blockhuys, Stéphanie; Holgersson, Stellan; Walton, Paul H; Wittung-Stafshede, Pernilla.

Afiliación

Zhang X; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
Walke GR; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
Horvath I; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
Kumar R; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
Blockhuys S; Department of Surgery, University of Gothenburg, 413 45 Gothenburg, Sweden.
Holgersson S; Department of Chemistry and Chemical Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
Walton PH; Department of Chemistry, University of York, Heslington, York YO10 5DD, United Kingdom.
Wittung-Stafshede P; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.

Proc Natl Acad Sci U S A ; 119(37): e2206905119, 2022 09 13.

Article en En | MEDLINE | ID: mdl-36067318

Asunto(s)

Proteínas Transportadoras de Cobre; Cobre; Péptidos y Proteínas de Señalización Intracelular; Metalochaperonas; Chaperonas Moleculares; Línea Celular Tumoral; Cobre/metabolismo; Proteínas Transportadoras de Cobre/genética; Proteínas Transportadoras de Cobre/metabolismo; Humanos; Péptidos y Proteínas de Señalización Intracelular/metabolismo; Iones/metabolismo; Metalochaperonas/genética; Metalochaperonas/metabolismo; Modelos Moleculares; Chaperonas Moleculares/genética; Chaperonas Moleculares/metabolismo; Oxidación-Reducción; Unión Proteica; Especies Reactivas de Oxígeno/metabolismo

Palabras clave

Atox1; Memo1; cancer; copper-binding protein; reactive oxygen species

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Chaperonas Moleculares / Cobre / Péptidos y Proteínas de Señalización Intracelular / Metalochaperonas / Proteínas Transportadoras de Cobre Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article País de afiliación: Suecia

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google