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Surgical Techniques and Nuances for Superior Cervical Ganglionectomy and Decentralization in Rats.
Madhani, Sarosh Irfan; Klein, David C; Muñoz, Estela M; Savastano, Luis E.
Afiliación
  • Madhani SI; Department of Neurosurgery, University of California, San Francisco, San Francisco, CA, USA.
  • Klein DC; Section on Neuroendocrinology, Intramural Research Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Muñoz EM; Laboratory of Neurobiology: Section of Chronobiology, Institute of Histology and Embryology of Mendoza (IHEM), National University of Cuyo, National Scientific and Technical Research Council (CONICET), Mendoza, Argentina.
  • Savastano LE; Department of Neurosurgery, University of California, San Francisco, San Francisco, CA, USA. luis.savastano@ucsf.edu.
Methods Mol Biol ; 2550: 53-62, 2022.
Article en En | MEDLINE | ID: mdl-36180677
ABSTRACT
The sympathetic nervous system has been implicated in various physiological and pathological processes, including regulation of homeostatic functions, maintenance of the circadian rhythms, and neuronal disruption and recovery after injury. Of special interest is focus on the role of the superior cervical ganglion (SCG) in regulating the daily changes in pineal function. Removal of the superior cervical ganglion (SCGx) and decentralization have served as valuable microsurgical models to investigate the effects of surgical denervation on this gland or organ. In this chapter, we offer information about methodologies for performing SCGx along with decentralization and denervation procedures, including details about recommended equipment as well as tips that can improve these techniques.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ganglionectomía / Ganglio Cervical Superior Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ganglionectomía / Ganglio Cervical Superior Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos