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CRISPR-based kinome-screening revealed MINK1 as a druggable player to rewire 5FU-resistance in OSCC through AKT/MDM2/p53 axis.
Mohanty, Sibasish; Mohapatra, Pallavi; Shriwas, Omprakash; Ansari, Shamima Azma; Priyadarshini, Manashi; Priyadarsini, Swatismita; Rath, Rachna; Sultania, Mahesh; Das Majumdar, Saroj Kumar; Swain, Rajeeb K; Dash, Rupesh.
Afiliación
  • Mohanty S; Institute of Life Sciences, Bhubaneswar, Odisha, 751023, India.
  • Mohapatra P; Regional Center for Biotechnology, Faridabad, India.
  • Shriwas O; Institute of Life Sciences, Bhubaneswar, Odisha, 751023, India.
  • Ansari SA; Regional Center for Biotechnology, Faridabad, India.
  • Priyadarshini M; Institute of Life Sciences, Bhubaneswar, Odisha, 751023, India.
  • Priyadarsini S; Institute of Life Sciences, Bhubaneswar, Odisha, 751023, India.
  • Rath R; Regional Center for Biotechnology, Faridabad, India.
  • Sultania M; Institute of Life Sciences, Bhubaneswar, Odisha, 751023, India.
  • Das Majumdar SK; KIIT School of Biotechnology, KIIT University, Bhubaneswar, India.
  • Swain RK; Institute of Life Sciences, Bhubaneswar, Odisha, 751023, India.
  • Dash R; Department of Oral & Maxillofacial Pathology, SCB Dental College & Hospital, Cuttack, Odisha, 753007, India.
Oncogene ; 41(45): 4929-4940, 2022 11.
Article en En | MEDLINE | ID: mdl-36182968
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Proteínas Proto-Oncogénicas c-akt Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: India
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Proteínas Proto-Oncogénicas c-akt Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: India