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Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma.
Hölting, Tilman L B; Cidre-Aranaz, Florencia; Matzek, Dana; Popper, Bastian; Jacobi, Severin J; Funk, Cornelius M; Geyer, Florian H; Li, Jing; Piseddu, Ignazio; Cadilha, Bruno L; Ledderose, Stephan; Zwilling, Jennifer; Ohmura, Shunya; Anz, David; Künkele, Annette; Klauschen, Frederick; Grünewald, Thomas G P; Knott, Maximilian M L.
Afiliación
  • Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Cidre-Aranaz F; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Matzek D; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Popper B; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Jacobi SJ; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Funk CM; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Geyer FH; Core Facility Animal Models, Biomedical Center, Ludwig-Maximilians-University, Planegg-Martinsried, Germany.
  • Li J; Core Facility Animal Models, Biomedical Center, Ludwig-Maximilians-University, Planegg-Martinsried, Germany.
  • Piseddu I; Department of General, Visceral and Transplant Surgery, University Hospital, LMU Munich, Munich, Germany.
  • Cadilha BL; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Ledderose S; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Zwilling J; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Ohmura S; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Anz D; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Künkele A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Klauschen F; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Grünewald TGP; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Knott MML; Division of Clinical Pharmacology, Department of Medicine IV, Klinikum der Universität München, Munich, Germany.
Mol Cancer ; 21(1): 199, 2022 10 13.
Article en En | MEDLINE | ID: mdl-36229873
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sarcoma / Sarcoma de Ewing Tipo de estudio: Prognostic_studies Límite: Child / Humans Idioma: En Revista: Mol Cancer Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sarcoma / Sarcoma de Ewing Tipo de estudio: Prognostic_studies Límite: Child / Humans Idioma: En Revista: Mol Cancer Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: Alemania