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Inhibition of RAS-driven signaling and tumorigenesis with a pan-RAS monobody targeting the Switch I/II pocket.
Wallon, Lauren; Khan, Imran; Teng, Kai Wen; Koide, Akiko; Zuberi, Mariyam; Li, Jianping; Ketavarapu, Gayatri; Traaseth, Nathaniel J; O'Bryan, John P; Koide, Shohei.
Afiliación
  • Wallon L; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016.
  • Khan I; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425.
  • Teng KW; Ralph H. Johnson VA Medical Center, Charleston, SC 29401.
  • Koide A; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016.
  • Zuberi M; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016.
  • Li J; Department of Medicine, New York University School of Medicine, New York, NY 10016.
  • Ketavarapu G; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425.
  • Traaseth NJ; Ralph H. Johnson VA Medical Center, Charleston, SC 29401.
  • O'Bryan JP; Department of Chemistry, New York University, New York, NY 10003.
  • Koide S; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016.
Proc Natl Acad Sci U S A ; 119(43): e2204481119, 2022 10 25.
Article en En | MEDLINE | ID: mdl-36252024
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Productos Biológicos / Proteínas Proto-Oncogénicas p21(ras) Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Productos Biológicos / Proteínas Proto-Oncogénicas p21(ras) Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article